Abstract: Voltage-gated sodium channels (VGSCs), formed by 24 transmembrane segments arranged into four domains, have a key role in the initiation and propagation of electrical signaling in excitable cells. VGSCs are involved in a variety [...]
Steroid injections, nerve stimulators and spinal fusions were no match for the chronic pain in Tammy Durfee's left side. After a decade searching for relief, a four-hour procedure using focused ultrasound put her pain to [...]
Pain-related diseases are the top leading causes of life disability. Identifying brain regions involved in persistent neuronal changes will provide new insights for developing efficient chronic pain treatment. Here, we showed that anterior nucleus of [...]
The present study investigated the effects of PA on a murine peripheral neuropathy model induced by intraperitoneal injection of paclitaxel and partial ligation of the sciatic nerve (Seltzer model), and identified its active ingredients.Read the [...]
Objective: To compare the analgesic effects of stimulation of the anterior cingulate cortex (ACC) or the posterior superior insula (PSI) against sham deep (d) repetitive (r) transcranial magnetic stimulation (TMS) in patients with central neuropathic [...]
Read articles about the latest pain research present at AAPM35 in Denver, March 6-10, 2019. View articles.
Source: JAMA Internal Medicine Gabapentin and pregabalin are the 2 clinically used medications in the gabapentinoid drug class. Pregabalin and gabapentin have both been approved by the US Food and Drug Administration for treatment of [...]
Source: PubMed.govRead more...
Source: PubMed.govRead more...
Source: PubMed.govRead more...
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