Anterior Nucleus of Paraventricular Thalamus Mediates Chronic Mechanical Hyperalgesia

Pain-related diseases are the top leading causes of life disability. Identifying brain regions involved in persistent neuronal changes will provide new insights for developing efficient chronic pain treatment. Here, we showed that anterior nucleus of paraventricular thalamus (PVA) plays an essential role in the development of mechanical hyperalgesia in neuropathic and inflammatory pain models in mice.  

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AAPM

American Academy of Pain Medicine