This section will include pain research in the news, general stories about research and findings, pain abstracts in the news, and PubMed abstracts

Hydromorphone Unit Dose Affects Intraoperative Dosing: An Observational Study

Although clinical factors related to intraoperative opioid administration have been described, there is little research evaluating whether administration is influenced by drug formulation and, specifically, the unit dose...
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Pregabalin and Gabapentin for Pain

Pregabalin and gabapentin can be effective as first line treatment for some people with neuropathic pain such as post-herpetic neuralgia and diabetic peripheral neuropathy.

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Whether Marijuana Helps with Pain is Unclear, Study Suggests

Medical marijuana users who say they have high levels of pain are more likely than those with low pain to say they use cannabis three or more times a day, according to a study published in the International Journal of Dr...
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Researchers Achieve Remote Control of Hormone Release

MIT researchers have now devised a way to remotely control the release of these hormones from the adrenal gland, using magnetic nanoparticles that could eventually offer a new way to treat hormone-linked disorders, inclu...
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Targeting Neurotrophic Factors: Novel Approaches to Musculoskeletal Pain

Chronic pain represents a substantial unmet medical need globally. In recent years, the quest for a new generation of novel, safe, mechanism-based analgesic treatments has focused on neurotrophic factors, a large group o...
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Loss of Nucleus Accumbens Low-Frequency Fluctuations Is a Signature of Chronic Pain

Chronic pain is a highly prevalent disease with poorly understood pathophysiology. In particular, the brain mechanisms mediating the transition from acute to chronic pain remain largely unknown. The authors identify a su...
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Unmet Needs in the Acute Treatment of Migraine Attacks and the Emerging Role of Calcitonin Gene–Related Peptide Receptor Antagonists

Migraine is a prevalent and chronic disease associated with high rates of disability and significant financial and socioeconomic burden. Current acute treatments for migraine attacks include both migraine-specific a...
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Complementary and Alternative Medicine for Postoperative Pain: A Systematic Review

The treatment of postoperative pain is an ongoing challenge for orthopaedic surgeons. Poorly controlled pain is associated with poorer patient outcomes, and the prescription of opioids may lead to prolonged, nonmedical u...
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Peripheral Trigeminal Branch Stimulation for Refractory Facial Pain: A Single-Center Experience

Facial pain refractory to medical treatments may benefit from neurosurgical interventions. Only a few studies have reported on the efficacy of peripheral trigeminal stimulation and more specifically supraorbital nerve (S...
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Spinal Glia and Proinflammatory Cytokines Mediate Mirror-Image Neuropathic Pain in Rats

Mirror-image allodynia is a mysterious phenomenon that occurs in association with many clinical pain syndromes. Allodynia refers to pain in response to light touch/pressure stimuli, which normally are perceived as innocu...
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The AAPM Annual Meeting offers education and networking opportunities for all members of the pain care team.

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