This section will include pain research in the news, general stories about research and findings, pain abstracts in the news, and PubMed abstracts

Using Mind Over Matter to Help Treat Chronic Pain

Researchers analyzed 21 randomized studies focusing on the effect of either cognitive behavioral therapy (CBT), to redirect pain-related thoughts and behaviors, or mindfulness-based stress reduction (MBSR), combining yoga and meditation to build awareness and acceptance of moment-to-moment experiences (including pain).

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The Effectiveness of Hypnosis for Pain Relief: A Systematic Review and Meta-Analysis of 85 Controlled Experimental Trials

The current meta-analysis aimed to quantify the effectiveness of hypnosis for reducing pain and identify factors that influence efficacy. Six major databases were systematically searched for trials comparing hypnotic inductions with no-intervention control conditions on pain ratings, threshold and tolerance using experimentally-evoked pain models in healthy participants. Random effects meta-analysis found analgesic effects of hypnosis for all pain outcomes.

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App-Based Multidisciplinary Back Pain Treatment Versus Combined Physiotherapy Plus Online Education: a Randomized Controlled Trial

Non-specific low back pain (LBP) is one of the leading causes of global disability. Multidisciplinary pain treatment (MPT) programs comprising educational, physical, and psychological interventions have shown positive treatment effects on LBP. Nonetheless, such programs are costly and treatment opportunities are often limited to specialized medical centers. mHealth and other digital interventions may be a promising method to successfully support patient self-management in LBP. To address these issues, we investigated the clinical effects of a multidisciplinary mHealth back pain App (Kaia App) in a randomized controlled trial (registered at German Clinical Trials Register under DRKS00016329).

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Biomarker for Chronic Fatigue Syndrome Identified by Stanford Researchers

People suffering from a debilitating disease known as chronic fatigue syndrome may soon have something they've been seeking for decades: scientific proof of their ailment. Researchers at the Stanford University School of Medicine have created a blood test that can flag the disease, which currently lacks a standard, reliable diagnostic test.

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The Case for Early Physical Therapy

Early use of physical therapy may be a promising non-pharmacologic strategy for patients with musculoskeletal pain. 

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Prehospital Analgesia With Intranasal Ketamine (PAIN-K): A Randomized Double-Blind Trial in Adults

We compare intranasal ketamine with intranasal placebo in providing pain reduction at 30 minutes when added to usual paramedic care with nitrous oxide. Methods: This was a randomized double-blind study of out-of-hospital patients with acute pain who reported a verbal numeric rating scale (VNRS) pain score greater than or equal to 5. Exclusion criteria were younger than 18 years, known ketamine intolerance, nontraumatic chest pain, altered mental status, pregnancy, and nasal occlusion. Patients received usual paramedic care and were randomized to receive either intranasal ketamine or intranasal saline solution at 0.75 mg/kg.

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The Role of Nonpharmacological Approaches to Pain Management: Proceedings of a Workshop

The Forum on Neuroscience and Nervous System Disorders and Global Forum on Innovation in Health Professional Education hosted a public workshop that discussed the state of evidence on the effectiveness of nonpharmacological treatments and integrative health models for pain management, multimodal approaches, and research gaps and key questions for further research. 

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Emotional Mirror Neurons in the Rat's Anterior Cingulate Cortex

How do the emotions of others affect us? The human anterior cingulate cortex (ACC) responds while experiencing pain in the self and witnessing pain in others, but the underlying cellular mechanisms remain poorly understood. Here we show the rat ACC (area 24) contains neurons responding when a rat experiences pain as triggered by a laser and while witnessing another rat receive footshocks. Most of these neurons do not respond to a fear-conditioned sound (CS).
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To Treat Pain Syndrome, Children's Mercy Doctors Try To Change How 'Brain Interprets Signals'

Hospital program offers intensive physical and occupational therapy, relaxation techniques, stress-management training, and music and therapeutic art to help manage Amplified Pain Syndrome.

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Assessing Study Quality and Bias in Prognosis Research on Rehabilitation in Chronic Pain Using the QUIPS Tool

Researchers performed a systematic review to synthesize evidence on prognostic factors for physical functioning after multidisciplinary rehabilitation in patients with chronic musculoskeletal pain and used a tool, QUIPS, which was developed specifically for evaluation of study quality of prognostic studies.

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The AAPM Annual Meeting offers education and networking opportunities for all members of the pain care team.

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