This section will include pain research in the news, general stories about research and findings, pain abstracts in the news, and PubMed abstracts

Prevention of Prescription Opioid Misuse and Projected Overdose Deaths in the United States

What is the projected effect of lowering incident nonmedical prescription opioid use on the future trajectory of the opioid overdose crisis in the United States? Read the abstract . 
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The Pain of Sleep Loss: A Brain Characterization in Humans

Sleep loss increases the experience of pain. However, the brain mechanisms underlying altered pain processing following sleep deprivation are unknown. Moreover, it remains unclear whether ecologically modest night-to-night changes in sleep, within an individual, confer consequential day-to-day changes in experienced pain. Here, we demonstrate that ...
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Gender Bias in Pediatric Pain Assessment

Accurate assessment of pain is central to diagnosis and treatment in healthcare, especially in pediatrics. However, few studies have examined potential biases in adult observer ratings of children's pain. Read the abstract . 

Penn’s ‘Enhanced Recovery’ Protocol Reduces Opioid Use in Spinal Surgery Patients

A new study published in the Journal of Neurosurgery: Spine showed that when an ERAS protocol was employed—which optimizes patients' surgical care before, during, and after surgery, including patient education, post-operative medications, and recovery plans—fewer patients needed pain medications one month after surgery. Full story
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Training the Prescriber: An Institutional Effort to Reduce the Amount of Opioids Prescribed Following Lumbar Surgery

A new study shows that an educational program on opiate use and misuse, the role of the orthopedic prescriber, multimodal analgesia, and state laws regarding opioid prescription could change prescriber behavior and result in a lower amount of prescribed opioids after lumbar surgery. Full story .
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Parents Worried About Risks, But Still Think Opioids Are Best for Kids’ Pain Relief, Nationwide Survey Shows

A new survey shows that parents remain conflicted about opioids: while more than half express concern their child may be at risk for opioid addiction, nearly two-thirds believe opioids are more effective at managing their child's pain after surgery or a broken bone than non-prescription medication or other alternatives. Full story .
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Research Pushes Back on Benefits of Compounded Topical Pain Creams

AAPM Board Member, Steven P. Cohen, MD , along with researchers at Johns Hopkins Medicine and Walter Reed National released the results of a rigorous federally funded study mandated by Congress that showed no statistically significant difference between relief offered by these creams and placebos. Full story .

The New York Times Features a Series of Articles on Pain in Children

​Part I: Managing Children's Pain After Surgery Part II: Taking the Pain Out of Children's Shots Part III: Helping Children Conquer Chronic Pain  

Benefits and Harms of Pregabalin in the Management of Neuropathic Pain: A Rapid Review and Meta-Analysis of Randomized Clinical Trials

Pregabalin has beneficial effects on some symptoms of neuropathic pain. However, its use significantly increases the risk of a number of adverse events and discontinuation due to adverse events. The quality of the evidence from journal publications is low. Read the abstract . 

Association of Pharmaceutical Industry Marketing of Opioid Products with Mortality From Opioid-Related Overdoses

This study identifies the association between direct-to-physician marketing of opioid products by pharmaceutical companies and mortality from prescription opioid overdoses across US counties. Read the abstract . 
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The AAPM Annual Meeting offers education and networking opportunities for all members of the pain care team.

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