Study Bolsters Patient-Controlled Analgesia for Cancer Pain

AAPM member Kenneth Candido, MD , comments on a study regarding patient-controlled analgesia (PCA) IV hydromorphone titration provides quicker analgesic effect, higher patient satisfaction and a similar tolerability comp...
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SARS-CoV-2 Spike protein co-opts VEGF-A/Neuropilin-1 receptor signaling to induce analgesia

Global spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues unabated. Binding of SARS-CoV-2's Spike protein to host angiotensin converting enzyme 2 triggers viral entry, but other proteins may...
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McGill Researchers End Decade-Long Search for Mechanical Pain Sensor

Researchers at McGill University have discovered that a protein found in the membrane of our sensory neurons are involved in our capacity to feel mechanical pain, laying the foundation for the development of powerful new...
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Trends in Prescription Analgesic Use Among Adults With Musculoskeletal Conditions in the United States, 1999-2016

Monitoring trends in prescription analgesic use among adults with musculoskeletal conditions provides insight into how changing prescribing practices, guidelines, and policy measures may affect those who need pain management. 

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Spinal Cord Stimulation Failure: Evaluation of Factors Underlying Hardware Explantation

Spinal cord stimulation has been shown to improve pain relief and reduce narcotic analgesic use in cases of complex refractory pain syndromes. However, a subset of patients ultimately undergoes removal of the spinal cord...
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Multimodal Analgesia With NSAID vs. Narcotics Alone After Shoulder Instability Surgery

This will be a single-center, prospective observational study. The study will compare post- operative pain scores and narcotic consumption between two groups of patients - one cohort will receive ibuprofen (Motrin) and P...
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Mole-Rat Pain Resistance Could Point the Way to New Analgesics

In a study published in Science , a team assessed the responses of eight kinds of mole-rats and two other rodent species to three substances that normally elicit pain: acid, capsaicin, and allyl isothiocyanate (AITC), th...
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