Patients undergoing the nerve preimplantation procedure had less pain than patients undergoing conventional amputations as measured by best, current, and residual pain scores. The nerve transplant group also experienced less phantom pain. Full story.
Regenerative science has advanced next-generation technologies from the research bench to potential clinical care options. But in the rigorous development of patient therapies, it is critical to validate the safety and efficacy of regenerative solutions. Full [...]
Atogepant, an investigational oral calcitonin gene-related peptide (CGRP) receptor antagonist for migraine prevention, led to fewer monthly migraine days in episodic monthly migraine patients, results of a phase IIb/III trial showed here. Full story.
Kailo Labs, an Utah-based nanotech startup, has launched the world's first nanotechnology-based bio-antenna for easy pain relief. Full story.
Sensory polyneuropathies, which are caused by dysfunction of peripheral sensory nerve fibers, are a heterogeneous group of disorders that range from the common diabetic neuropathy to the rare sensory neuronopathies. The presenting symptoms, acuity, time [...]
A naturally occurring enzyme, called diacylglycerol lipase-beta, or DAGLb, is a possible new drug target for reducing pain. Full story.
To determine the risk of prolonged opioid use in patients receiving tramadol compared with other short acting opioids. Opioid-naive patients undergoing elective surgery. Risk of persistent opioid use after discharge for patients treated with tramadol [...]
Hospitals are experimenting with virtual reality to see if it can reduce pain, enhance the effect of medication, and lower the chances a patient is admitted. Full story.
There is a significant unmet need for novel effective well‐tolerated acute migraine treatments. REN is a novel acute migraine treatment that stimulates upper arm peripheral nerves to induce conditioned pain modulation – an endogenous analgesic [...]
A novel opioid developed by researchers at Tulane University and the Southeast Louisiana Veterans Health Care System is as strong as morphine but isn't addictive and causes fewer side effects, according to a new study [...]
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