Trends in Prescription Opioid Use and Dose Trajectories Before Opioid Use Disorder or Overdose in US Adults From 2006 to 2016: A Cross-Sectional Study

With governments’ increasing efforts to curb opioid prescription use and limit dose below the Centers for Disease Control and Prevention (CDC)-recommended threshold of 90 morphine milligram equivalents per day, little is known about prescription opioid patterns preceding opioid use disorder (OUD) or overdose.

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