This section will include pain research in the news, general stories about research and findings, pain abstracts in the news, and PubMed abstracts

Effect of Ubrogepant vs Placebo on Pain and the Most Bothersome Associated Symptom in the Acute Treatment of Migraine

 Is ubrogepant, an oral calcitonin gene–related peptide receptor antagonist, effective in the acute treatment of migraine?

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Can AI Fix Your Bad Back?

At Cleveland Clinic and elsewhere, clinicians and data scientists are taking steps to leverage AI to improve patient outcomes while reducing healthcare costs, particularly among candidates for surgical care.

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AI

A New Link Between Migraines, Opioid Overuse May Be Key to Treating Pain

Researchers at the University of Illinois at Chicago and colleagues discovered that a peptide — small chains of amino acids that can regulate many behaviors and brain signaling pathways — links together migraine pain and...
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Yoga and Physical Therapy as Treatment for Chronic Lower Back Pain also Improves Sleep

Yoga and physical therapy (PT) are effective approaches to treating co-occurring sleep disturbance and back pain while reducing the need for medication, according to a new study. The research showed significant improveme...
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New Discovery: How Chronic Pain Changes Your Brain and Personality

Australian researchers have found that people with chronic pain experience physical alterations in their brain that likely leads to negative changes in their personality. The study discovered that people with chronic pai...
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Fighting Opioids with an Unlikely Supplemental Painkiller: Anti-Itch Medicine

  A West Virginia University researcher is investigating whether an anti-itch medication that targets a specific part of our nerve cells can make morphine—which targets a different part—more effective.

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Safety and Efficacy of Sphenopalatine Ganglion Stimulation for Chronic Cluster Headache: A Double-Blind, Randomized Controlled Trial

Chronic cluster headache is the most disabling form of cluster headache. The mainstay of treatment is attack prevention, but the available management options have little efficacy and are associated with substantial side-...
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Selective Modulation of Tonic Aversive Qualities of Neuropathic Pain by Morphine in the Central Nucleus of the Amygdala Requires Endogenous Opioid Signaling in the Anterior Cingulate Cortex

The amygdala is a key subcortical region thought to contribute to emotional components of pain. As opioid receptors are found in both the central (CeA) and basolateral (BLA) nuclei of the amygdala, we investigated the ef...
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Self-Reported Prescription Drug Use for Pain and for Sleep and Incident Frailty

This study aimed to estimate incident frailty risks of prescription drugs for pain and for sleep in older US adults. 

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Trends and Rapidity of Dose Tapering Among Patients Prescribed Long-Term Opioid Therapy, 2008-2017

How often are patients who are prescribed long-term opioids undergoing tapering of their daily doses, and how often do patients undergo a rapid taper rate? Read the abstract.
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The AAPM Annual Meeting offers education and networking opportunities for all members of the pain care team.

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