This section will include pain research in the news, general stories about research and findings, pain abstracts in the news, and PubMed abstracts

Interleukin-10 Resolves Pain Hypersensitivity Induced by Cisplatin by Reversing Sensory Neuron Hyperexcitability

Understanding the mechanisms that drive transition from acute to chronic pain is essential to identify new therapeutic targets. The importance of endogenous resolution pathways acting as a "brake" to prevent development ...
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Development and Validation of a Prediction Tool for Pain Reduction in Adult Patients Undergoing Elective Lumbar Spinal Fusion: a Multicentre Cohort Study

On average, 56% of patients report a clinically relevant reduction in pain after lumbar spinal fusion (LSF). Preoperatively identifying which patient will benefit from LSF is paramount to improve clinical decision making...
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Vacuum myofascial therapy device for non-specific neck pain: A single blind randomized clinical trial

This study aimed to investigate the efficacy of a vacuum myofascial therapy device (VT) for improving pressure pain thresholds (PPTs), range of motion (ROM), neck pain-related disability, pain, and quality of life in pat...
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Specially Designed Footwear Reduces Pain of Knee Osteoarthritis

Wearing shoes specifically designed with a novel sole (biomechanical footwear) significantly reduces the pain associated with knee osteoarthritis, according to findings in JAMA

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Nerve Stimulation Helps Manage Pain Without Opioids

Researchers use a new technique that uses an injectable liquid polymer that cures – like household epoxy -- next to or around the target nerve. This device provides a localized stimulus that avoids the side effects of ot...
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Neurobiologist Finds Potent Pain-Suppression Center in the Brain

A Duke University research team has found a small area of the brain in mice that can profoundly control the animals' sense of pain. The researchers found that general anesthesia also activates a specific subset of inhibi...
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Effect of Yoga as Add-On Therapy in Migraine

This abstract evaluated the effectiveness of yoga as an adjuvant to conventional medical management on clinical outcomes in patients with migraine. 

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Sigma-1 Receptor Activity in Primary Sensory Neurons Is a Critical Driver of Neuropathic Pain

The Sigma-1 receptor (σ1R) is highly expressed in the primary sensory neurons (PSNs) that are the critical site of initiation and maintenance of pain following peripheral nerve injury.  

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The Comparative Effectiveness of Physical Exercise Interventions in Individuals With Chronic Non-Specific Neck Pain: Protocol for a Network Meta-Analysis

Neck pain is a global burdensome problem, with a large proportion of neck pain cases becoming chronic. Although physical exercise is a commonly prescribed treatment, the evidence on the effectiveness of isolated exercise...
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How to Manage Chronic Pain, Opioid Addiction During COVID-19

A Rutgers emergency medicine expert discusses challenges faced by chronic pain sufferers and people recovering from addiction during this period of social distancing. 

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The AAPM Annual Meeting offers education and networking opportunities for all members of the pain care team.

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