This section will include pain research in the news, general stories about research and findings, pain abstracts in the news, and PubMed abstracts

Voltage-gated Sodium Channels: Structures, Functions, and Molecular Modeling

Abstract: Voltage-gated sodium channels (VGSCs), formed by 24 transmembrane segments arranged into four domains, have a key role in the initiation and propagation of electrical signaling in excitable cells. VGSCs are involved in a variety of diseases, including epilepsy, cardiac arrhythmias, and neuropathic pain, and therefore have been regarded as appealing therapeutic targets for the development of anticonvulsant, antiarrhythmic, and local anesthetic drugs.

Continue reading

Medical Schools Look to Educate the Next Generation of Doctors on Pain

WBUR public radio interview discusses how some medical schools are changing the way students learn about pain and addiction.  Full story.  
Topics:

Walking Without Pain: How a New Surgical Procedure is Giving Hope to Some Amputees

An amputee recently became the third patient in Canada to undergo osseointegration, a relatively new procedure aimed at giving amputees higher functionality, mobility and comfort. Full story.  
Topics:

Study Shows Safety Initiative Decreases Opioid Use in VA Patients with Little Impact on Pain Scores

New research published in Anesthesiology reports that after an Opioid Safety Initiative (OSI) was implemented at the Veterans Health Administration, patients undergoing knee replacement surgery were prescribed significan...
Continue reading

Can Tech 'Objectively' Assess Pain?

Some combination of data and machinery may, go the pronouncements of the tech world, do what millennia of humans have been unable to: accurately feel someone else's pain.  Full story.  

In Lab, SLU Researchers Flip Pain Switch in Spinal Cord Cells

Facing an urgent need for safer and more effective therapies for those suffering from debilitating pain, Saint Louis University researchers are on a mission to find a non-narcotic off-switch for pain.  Full story. &...
Continue reading

Multiple Brain Regions Moderate and Link Depressive Mood and Pain

  Researchers at University of California San Diego School of Medicine have identified specific regions of the brain that drive, influence, and moderate depressive mood and its relationship to perceiving physical pa...
Continue reading
Topics:

Efficacy of Headache Treatment Using Radiofrequency Ablation

Despite the availability of therapies, many headache syndromes remain refractory to symptomatic treatment, achieving incomplete resolution of pain, and patients with chronic headaches often pursue nonpharmacologic treatm...
Continue reading

Targeted Muscle Reinnervation Reduces Limb Pain After Amputation

Patients undergoing the nerve preimplantation procedure had less pain than patients undergoing conventional amputations as measured by best, current, and residual pain scores. The nerve transplant group also experienced ...
Continue reading

Mayo Clinic Orthopedist Shares Perspective on Regenerative Medicine

Regenerative science has advanced next-generation technologies from the research bench to potential clinical care options. But in the rigorous development of patient therapies, it is critical to validate the safety and e...
Continue reading

The AAPM Annual Meeting offers education and networking opportunities for all members of the pain care team.

Learn More