A protein called RGS4 (Regulator of G protein signaling 4) plays a prominent role in the maintenance of long-term pain states and may serve as a promising new target for the treatment of chronic pain conditions, accordin...
This section will include pain research in the news, general stories about research and findings, pain abstracts in the news, and PubMed abstracts
Intra-articular injections of corticosteroids for relief of the pain of hip or knee osteoarthritis (OA) may have adverse long-term consequences, researchers suggested. Full story.
Brain scans focusing on spatial variations in cerebral blood flow correlated with the presence -- though not severity -- of chronic knee pain, researchers said. The findings could eventually lead to a "brain signature of...
A new study in mice uncovered a previously unknown role that the central amygdala can play in upgrading or downgrading pain signals in the brain's circuitry. The study, published in Cell Reports , was conducted by resear...
Early life stress (ELS) can significantly influence biological pathways associated with nociception, increasing vulnerability to future heightened pain sensitivity and subsequent risk of pain events. However, very little...
A team of Australian-led researchers has discovered a uniquely shaped fungus in pristine waters, which may mimic opioids with fewer side-effects. It had been hoped that such a molecular structure might exist. Full...
The medical community is turning to other approaches for chronic pain, including increasing patient support and education and improving overall wellness, perhaps with alternative treatments. Full story.
Abstract: BACKGROUND: One-size-fits-all interventions reduce chronic low back pain (CLBP) a small amount. An individualised intervention called cognitive functional therapy (CFT) was superior for CLBP c...
A new study, published in the journal Nature Human Behavior , finds that patients can pick up on subtle facial cues from doctors. The study reveals that the doctor's belief in how effective a treatment will be can have a...
Abstract: The goal of this narrative review was to give an up-to-date overview of the peripheral and central neurostimulation methods that can be used to treat chronic pain. Special focus has been given to three pa...