We evaluated whether the rate of incident chronic opioid use is higher in obese patients with rheumatoid arthritis (RA). Full story .

A study led by University of Kentucky Markey Cancer Center researchers showed that patients who already used opioids, sedatives or antidepressants prior to colorectal surgery experience significantly more complications p...

Pinhole incision enables blocking of blood supply to an inflamed joint, providing long-term relief. Full story .

  Delta opioid receptors have a built-in mechanism for pain relief and can be precisely targeted with drug-delivering nanoparticles—making them a promising target for treating chronic inflammatory pain with fewer si...

Researchers at The University of New Mexico (UNM) showed that legal Cannabis hemp oil reduced mechanical pain sensitivity 10-fold for several hours in mice with chronic post-operative neuropathic pain. Full story .  ...

A new microanatomical study investigated in detail spatial arrangements of the nerve fibers and blood vessels in the ear to position the electrodes in the ear. Until now, physicians had to rely on experience to place the...

According to a review paper from McGill University published in Nature Reviews Neuroscience , most pain research remains overwhelmingly based on the study of male rodents, continuing to test hypotheses derived from earli...

There is histological evidence of microstructural changes in the zygomaticotemporal branch of the trigeminal nerve in migraineurs. This raises the possibility that altered trigeminal nerve properties contribute to migrai...

The belief that weather influences people's health has been prevalent for millennia. Recent studies on the relationship between weather and pain for those who suffer from chronic pain remain indeterminate, with some stud...

The cytokine, interleukin-23 (IL-23), can be critical for the progression of inflammatory diseases, including arthritis, and is often associated with T lymphocyte biology. We previously showed that certain lymphocyte-ind...