This section will include pain research in the news, general stories about research and findings, pain abstracts in the news, and PubMed abstracts

Mount Sinai Researchers Identify Brain Protein That Promotes Maintenance of Chronic Pain

A protein called RGS4 (Regulator of G protein signaling 4) plays a prominent role in the maintenance of long-term pain states and may serve as a promising new target for the treatment of chronic pain conditions, accordin...
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Joint Injections: Are They Worth the Risk?

Intra-articular injections of corticosteroids for relief of the pain of hip or knee osteoarthritis (OA) may have adverse long-term consequences, researchers suggested.   Full story.

Objective Marker of Chronic Pain on the Horizon

Brain scans focusing on spatial variations in cerebral blood flow correlated with the presence -- though not severity -- of chronic knee pain, researchers said. The findings could eventually lead to a "brain signature of...
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NIH Study in Mice Explains How Brain Can Turn Pain Signals Up or Down

A new study in mice uncovered a previously unknown role that the central amygdala can play in upgrading or downgrading pain signals in the brain's circuitry. The study, published in Cell Reports , was conducted by resear...
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The Association of Early Life Stressors with Pain Sensitivity and Pain Experience at 22 Years

Early life stress (ELS) can significantly influence biological pathways associated with nociception, increasing vulnerability to future heightened pain sensitivity and subsequent risk of pain events. However, very little...
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Estuarine Waters Hold Promise in Global Pain-Relief Hunt

  A team of Australian-led researchers has discovered a uniquely shaped fungus in pristine waters, which may mimic opioids with fewer side-effects. It had been hoped that such a molecular structure might exist. Full...
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Chronic Pain is a Huge Problem Nationwide, it’s Time for Fresh Approaches

  The medical community is turning to other approaches for chronic pain, including increasing patient support and education and improving overall wellness, perhaps with alternative treatments. Full story.

Cognitive Functional Therapy Compared With a Group-Based Exercise and Education Intervention for Chronic Low Back Pain: A Multicentre Randomised Controlled Trial

  Abstract: BACKGROUND:  One-size-fits-all interventions reduce chronic low back pain (CLBP) a small amount. An individualised intervention called cognitive functional therapy (CFT) was superior for CLBP c...
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The Placebo Effect Works and You Can Catch It From Your Doctor

A new study, published in the journal Nature Human Behavior , finds that patients can pick up on subtle facial cues from doctors. The study reveals that the doctor's belief in how effective a treatment will be can have a...
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Neurostimulation Methods in the Treatment of Chronic Pain

Abstract:  The goal of this narrative review was to give an up-to-date overview of the peripheral and central neurostimulation methods that can be used to treat chronic pain. Special focus has been given to three pa...
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