This section will include pain research in the news, general stories about research and findings, pain abstracts in the news, and PubMed abstracts

Smokers Are At High Risk for Low Back Pain, Hospitalization, and Opioid Use

Smokers are at high risk for low back pain, and also have higher rates of healthcare utilization and opioid use, and physicians should ask these patients about other comorbidities that may make their pain treatment more ...
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Virtual Reality Intervention Shows Promise for Back Pain Patients Who Are Afraid to be Active

A new virtual reality physical activity intervention may be effective for people with chronic low back pain who avoid activity because of fear, helping them to become physically active once again, according to a new stud...
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Two Decades of Data Reveal Overall Increase in Pain, Opioid Use Among U.S. Adults

Recent NIH study provides new insights concerning pain trends and opioid use for pain management.

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Effects of Microencapsulated Olfactory Ensheathing Cell Transplantation on Neuropathic Pain and P2X7 Receptor Expression in the L4-5 Spinal Cord Segment

The aim of this study was to determine the role of microencapsulated olfactory ensheathing cell (MC-OEC) transplantation in rats with sciatic nerve injury-induced pain, and its relationship with P2 × 7 receptor expressio...
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Stimulating the Vagus Nerve in the Neck Might Help Ease Pain Associated with PTSD

In a randomized, controlled pilot trial, participants pre-treated with noninvasive vagus nerve stimulation experienced less pain after heat stimulus than mock-treated participants.

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Assessment of the FDA Risk Evaluation and Mitigation Strategy for Transmucosal Immediate-Release Fentanyl Products

Transmucosal immediate-release fentanyls (TIRFs), indicated solely for breakthrough cancer pain in opioid-tolerant patients, are subject to a US Food and Drug Administration (FDA) Risk Evaluation and Mitigation Strategy ...
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Use of Prescription Opioids and Initiation of Fatal 2-Vehicle Crashes

The prevalence of prescription opioids detected in fatally injured drivers has increased markedly in the past 2 decades in the United States. It is unclear whether driver use of prescription opioids plays a role in fatal...
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A New Painkiller Nanomedicine to Bypass the Blood-Brain Barrier and the Use of Morphine

The clinical use of endogenous neuropeptides has historically been limited due to pharmacokinetic issues, including plasma stability and blood-brain barrier permeability. In this study, we show that the rapidly metaboliz...
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Predicting Inadequate Postoperative Pain Management in Depressed Patients: A Machine Learning Approach

Widely-prescribed prodrug opioids (e.g., hydrocodone) require conversion by liver enzyme CYP-2D6 to exert their analgesic effects. The most commonly prescribed antidepressant, selective serotonin reuptake inhibitors (SSR...
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Prevention of Prescription Opioid Misuse and Projected Overdose Deaths in the United States

What is the projected effect of lowering incident nonmedical prescription opioid use on the future trajectory of the opioid overdose crisis in the United States?

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The AAPM Annual Meeting offers education and networking opportunities for all members of the pain care team.

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