This section will include pain research in the news, general stories about research and findings, pain abstracts in the news, and PubMed abstracts

Researchers Devise Decoy Molecule to Block Pain Where It Starts

Source: University of Texas Dallas For anyone who has accidentally injured themselves, Dr. Zachary Campbell not only sympathizes, he's developing new ways to blunt pain. Campbell's team took the approach of blocking the creation of the proteins that set pain in motion. After an injury, instructions provided by the genome — the full set of genetic i...
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Rapid Turnover of Cortical NCAM1 Regulates Synaptic Reorganization after Peripheral Nerve Injury

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Intrathecal Morphine Microdose Method Sensory Changes

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Prescription Opioid Use and Satisfaction with Care among Adults with Musculoskeletal Conditions

[Source: Annals of Family Medicine] Abstract: Purpose: In the current payment paradigm, reimbursement is partially based on patient satisfaction scores. We sought to understand the relationship between prescription opioid use and satisfaction with care among adults who have musculoskeletal conditions. Read more...
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Power Transmission and Workload Balancing Policies in Ehealth Mobile Cloud Computing Scenarios: a Real IoT Ehealth Scenario for and Prediction of the Migraine Disease Is Shown

Source: Future Generation Computer Systems Abstract: The Internet of Things (IoT) holds big promises for healthcare, especially in proactive personal eHealth. Prediction of symptomatic crises in chronic diseases in the IoT scenario leads to the deployment of ambulatory monitoring systems. These systems place a major concern in the amount of data to...
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University of Michigan/Wayne State Chronic Pain Study

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Scientists Take a Big Step Toward Building a Better Opioid

Source: University of North Carolina School of Medicine For the first time, scientists at the University of North Carolina School of Medicine and collaborators solved the crystal structure of the activated kappa opioid receptor bound to a morphine derivative. They then created a new drug-like compound that activates only that receptor, a key step i...
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Gabapentinoid Use in the United States 2002 through 2015 (Research Letter)

Source: JAMA Internal Medicine Gabapentin and pregabalin are the 2 clinically used medications in the gabapentinoid drug class. Pregabalin and gabapentin have both been approved by the US Food and Drug Administration for treatment of partial seizures and postherpetic neuralgia. Gabapentin enacarbil has also been approved for restless legs syndrome,...
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Reduction of Opioid Use and Improvement in Chronic Pain in Opioid-Experienced Patients After Topical Analgesic Treatment: An Exploratory Analysis

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The Appropriate Use of Opioids in the Treatment of Refractory Restless Legs Syndrome

Source: Mayo Clinic Proceedings Abstract: Restless legs syndrome (RLS) is a distinct disorder, differing from chronic pain in many ways. Refractory RLS is characterized by unresponsiveness to dopamine agonists or alpha-2-delta ligands due to inadequate efficacy, augmentation, or adverse effects. This may result in severely impaired quality of life,...
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The AAPM Annual Meeting offers education and networking opportunities for all members of the pain care team.

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