This section will include pain research in the news, general stories about research and findings, pain abstracts in the news, and PubMed abstracts

Clinical Practice Guidelines for Neck and Low Back Pain in Outpatient Physical Therapy

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Less is More When it Comes to Prescription Opioids for Hospital Patients, Study Finds

Source: Yale School of Medicine In a pilot study published in JAMA Internal Medicine , Yale researchers significantly reduced doses of opioid painkillers given to hospital patients. By delivering the opioids with a shot ...
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Top-Down Descending Facilitation of Spinal Sensory Excitatory Transmission from the Anterior Cingulate Cortex

Source: Nature Communications Abstract: Spinal sensory transmission is under descending biphasic modulation, and descending facilitation is believed to contribute to chronic pain. Descending modulation from the brainstem...
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Development and Course of Chronic Pain Over 4 Years in the General Population: The HUNT Pain Study

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Acetaminophen Versus IV Hydromorphone for Pain in the Elderly in the ED

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Drosophila Insulin Receptor Regulates the Persistence of Injury-Induced Nociceptive Sensitization

Source: Disease Models & Mechanisms Diabetes-associated nociceptive hypersensitivity affects diabetic patients with hard-to-treat chronic pain. Because multiple tissues are affected by systemic alterations in insulin...
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Body’s 'Natural Opioids' Affect Brain Cells Much Differently than Morphine

Source: University of California, San Francisco A new study led by UC San Francisco scientists shows that brain cells, or neurons, react differently to opioid substances created inside the body – the endorphins responsib...
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Vertebroplasty Versus Sham Procedure for Painful Acute Osteoporotic Vertebral Compression Fractures (VERTOS IV): Randomised Sham Controlled Clinical Trial

Source: BMJ Abstract: Objective: To assess whether percutaneous vertebroplasty results in more pain relief than a sham procedure in patients with acute osteoporotic compression fractures of the vertebral body. Conclusion...
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Selecting Effective Combinations of Treatment for Low Back Pain (SELECT LBP)

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Association Between Prescription Drug Monitoring Programs and Nonfatal and Fatal Drug Overdoses: A Systematic Review

Source: Annals of Internal Medicine Abstract: Background: Prescription drug monitoring programs (PDMPs) are a key component of the president's Prescription Drug Abuse Prevention Plan to prevent opioid overdoses in the Un...
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