According to a review paper from McGill University published in Nature Reviews Neuroscience , most pain research remains overwhelmingly based on the study of male rodents, continuing to test hypotheses derived from earli...
This section will include pain research in the news, general stories about research and findings, pain abstracts in the news, and PubMed abstracts
There is histological evidence of microstructural changes in the zygomaticotemporal branch of the trigeminal nerve in migraineurs. This raises the possibility that altered trigeminal nerve properties contribute to migrai...
The belief that weather influences people's health has been prevalent for millennia. Recent studies on the relationship between weather and pain for those who suffer from chronic pain remain indeterminate, with some stud...
The cytokine, interleukin-23 (IL-23), can be critical for the progression of inflammatory diseases, including arthritis, and is often associated with T lymphocyte biology. We previously showed that certain lymphocyte-ind...
Understanding the mechanisms that drive transition from acute to chronic pain is essential to identify new therapeutic targets. The importance of endogenous resolution pathways acting as a "brake" to prevent development ...
On average, 56% of patients report a clinically relevant reduction in pain after lumbar spinal fusion (LSF). Preoperatively identifying which patient will benefit from LSF is paramount to improve clinical decision making...
This study aimed to investigate the efficacy of a vacuum myofascial therapy device (VT) for improving pressure pain thresholds (PPTs), range of motion (ROM), neck pain-related disability, pain, and quality of life in pat...
Wearing shoes specifically designed with a novel sole (biomechanical footwear) significantly reduces the pain associated with knee osteoarthritis, according to findings in JAMA.
Researchers use a new technique that uses an injectable liquid polymer that cures – like household epoxy -- next to or around the target nerve. This device provides a localized stimulus that avoids the side effects of ot...
A Duke University research team has found a small area of the brain in mice that can profoundly control the animals' sense of pain. The researchers found that general anesthesia also activates a specific subset of inhibi...