This section will include pain research in the news, general stories about research and findings, pain abstracts in the news, and PubMed abstracts

The Association Between Antidepressant Treatment and Brain Connectivity in Two Double-Blind, Placebo-Controlled Clinical Trials: A Treatment Mechanism Study

Antidepressant medications offer an effective treatment for depression, yet nearly 50% of patients either do not respond or have side-effects rendering them unable to continue the course of treatment. Mechanistic studies...
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Prevalence and Risk Factors Associated With Long-Term Opioid Use After Injury Among Previously Opioid-Free Workers.

Using opioids for acute pain can lead to long-term use and associated morbidity and mortality. Injury has been documented as a gateway to long-term opioid use in some populations, but data are limited for injured workers.

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Shifting Brain Circuits in Pain Chronicity

The evaluation of brain changes to a specific pain condition in pediatric and adult patients allows for insights into potential mechanisms of pain chronicity and possibly long-term brain changes. Here we focused on the p...
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Evaluation of Clinical Outcomes in an Interdisciplinary Abdominal Pain Clinic: A Retrospective, Exploratory Review

Pediatric functional gastrointestinal disorders (FGIDs) are common and well-accepted to be etiologically complex in terms of the contribution of biological, psychological, and social factors to symptom presentations. Non...
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Managing Cluster Headache

Cluster headache is a neurological disorder that presents with unilateral severe headache associated with ipsilateral cranial autonomic symptoms. Cluster headache attacks often occur more than once a day, and typically m...
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Does Disordered Sleep Moderate the Relationship Between Pain, Disability, and Downstream Healthcare Utilization in Patients with Low Back Pain? A Longitudinal Cohort from the US Military Health System

The purpose was to evaluate the influence of disordered sleep on the relationship between pain and healthcare utilization (HCU) and pain-related disability and HCU in individuals with low back pain (LBP).

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Rimegepant, an Oral Calcitonin Gene–Related Peptide Receptor Antagonist, for Migraine

Calcitonin gene–related peptide receptor has been implicated in the pathogenesis of migraine. Rimegepant is an orally administered, small-molecule, calcitonin gene–related peptide receptor antagonist that may be effective in acute migraine treatment.

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Thwack! Insects Feel Chronic Pain After Injury

A study in the peer-reviewed journal Science Advances offers the first genetic evidence of what causes chronic pain in fruit flies and there is good evidence that similar changes also drive chronic pain in humans. Full s...
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Rehab with Robots

A new generation of robotics is helping debilitated patients regain much of their former abilities by using technology that essentially communicates with muscles when the brain cannot. 

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Combined Online Self-Management for Pain, Associated Anxiety, and Depression Works

In a new paper published in the Journal of General Internal Medicine , researchers report that online symptom self-management works to decrease pain, anxiety, and depression symptoms. They also found that online symptom ...
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The AAPM Annual Meeting offers education and networking opportunities for all members of the pain care team.

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