Antidepressant medications offer an effective treatment for depression, yet nearly 50% of patients either do not respond or have side-effects rendering them unable to continue the course of treatment. Mechanistic studies...
This section will include pain research in the news, general stories about research and findings, pain abstracts in the news, and PubMed abstracts
Using opioids for acute pain can lead to long-term use and associated morbidity and mortality. Injury has been documented as a gateway to long-term opioid use in some populations, but data are limited for injured workers.
The evaluation of brain changes to a specific pain condition in pediatric and adult patients allows for insights into potential mechanisms of pain chronicity and possibly long-term brain changes. Here we focused on the p...
Pediatric functional gastrointestinal disorders (FGIDs) are common and well-accepted to be etiologically complex in terms of the contribution of biological, psychological, and social factors to symptom presentations. Non...
Cluster headache is a neurological disorder that presents with unilateral severe headache associated with ipsilateral cranial autonomic symptoms. Cluster headache attacks often occur more than once a day, and typically m...
The purpose was to evaluate the influence of disordered sleep on the relationship between pain and healthcare utilization (HCU) and pain-related disability and HCU in individuals with low back pain (LBP).
Calcitonin gene–related peptide receptor has been implicated in the pathogenesis of migraine. Rimegepant is an orally administered, small-molecule, calcitonin gene–related peptide receptor antagonist that may be effective in acute migraine treatment.
A study in the peer-reviewed journal Science Advances offers the first genetic evidence of what causes chronic pain in fruit flies and there is good evidence that similar changes also drive chronic pain in humans. Full s...
A new generation of robotics is helping debilitated patients regain much of their former abilities by using technology that essentially communicates with muscles when the brain cannot.
In a new paper published in the Journal of General Internal Medicine , researchers report that online symptom self-management works to decrease pain, anxiety, and depression symptoms. They also found that online symptom ...