This section will include pain research in the news, general stories about research and findings, pain abstracts in the news, and PubMed abstracts

Study Shows Safety Initiative Decreases Opioid Use in VA Patients with Little Impact on Pain Scores

New research published in Anesthesiology reports that after an Opioid Safety Initiative (OSI) was implemented at the Veterans Health Administration, patients undergoing knee replacement surgery were prescribed significan...
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Can Tech 'Objectively' Assess Pain?

Some combination of data and machinery may, go the pronouncements of the tech world, do what millennia of humans have been unable to: accurately feel someone else's pain.  Full story.  

In Lab, SLU Researchers Flip Pain Switch in Spinal Cord Cells

Facing an urgent need for safer and more effective therapies for those suffering from debilitating pain, Saint Louis University researchers are on a mission to find a non-narcotic off-switch for pain.  Full story. &...
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Multiple Brain Regions Moderate and Link Depressive Mood and Pain

  Researchers at University of California San Diego School of Medicine have identified specific regions of the brain that drive, influence, and moderate depressive mood and its relationship to perceiving physical pa...
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Efficacy of Headache Treatment Using Radiofrequency Ablation

Despite the availability of therapies, many headache syndromes remain refractory to symptomatic treatment, achieving incomplete resolution of pain, and patients with chronic headaches often pursue nonpharmacologic treatm...
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Targeted Muscle Reinnervation Reduces Limb Pain After Amputation

Patients undergoing the nerve preimplantation procedure had less pain than patients undergoing conventional amputations as measured by best, current, and residual pain scores. The nerve transplant group also experienced ...
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Mayo Clinic Orthopedist Shares Perspective on Regenerative Medicine

Regenerative science has advanced next-generation technologies from the research bench to potential clinical care options. But in the rigorous development of patient therapies, it is critical to validate the safety and e...
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Oral CGRP Drug Bests Placebo for Migraine Prevention

Atogepant, an investigational oral calcitonin gene-related peptide (CGRP) receptor antagonist for migraine prevention, led to fewer monthly migraine days in episodic monthly migraine patients, results of a phase IIb/III ...
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Diagnosis and Management of Sensory Polyneuropathy

 Sensory polyneuropathies, which are caused by dysfunction of peripheral sensory nerve fibers, are a heterogeneous group of disorders that range from the common diabetic neuropathy to the rare sensory neuronopathies. The presenting symptoms, acuity, time course, severity, and subsequent morbidity vary and depend on the type of fiber that is affected and the underlying cause. Damage to small thinly myelinated and unmyelinated nerve fibers results in neuropathic pain, whereas damage to large myelinated sensory afferents results in proprioceptive deficits and ataxia.
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Chemist IDs Possible Addiction-Free Pain Reliever

 A naturally occurring enzyme, called diacylglycerol lipase-beta, or DAGLb, is a possible new drug target for reducing pain. Full story.  

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