This section will include pain research in the news, general stories about research and findings, pain abstracts in the news, and PubMed abstracts

Initial Opioid Prescriptions among U.S. Commercially Insured Patients, 2012–2017

 Background: The United States is undergoing a crippling opioid epidemic, spurred in part by overuse of prescription opioids by adults 25 to 64 years of age. Of concern are long-duration and high-dose initial prescriptions, which place the patients and their friends and relatives at heightened risk for long-term opioid use, misuse, overdose, and death.
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Pain-Induced Negative Affect Is Mediated via Recruitment of the Nucleus Accumbens Kappa Opioid System.

 Negative affective states affect quality of life for patients suffering from pain. These maladaptive emotional states can lead to involuntary opioid overdose and many neuropsychiatric comorbidities. Uncovering the ...
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Trends and Patterns of Geographic Variation in Opioid Prescribing Practices by State, United States, 2006-2017

Importance : Risk of opioid use disorder, overdose, and death from prescription opioids increases as dosage, duration, and use of extended-release and long-acting formulations increase. States are well suited to respond ...
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New Target for Chronic Pain Relief Confirmed by Scientists

A research group at Hiroshima University observed a potential new target for chronic pain treatment. Further research using this receptor could lead to new, more effective drugs to use in pain-relieving treatment for chronic pain. 

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Where Does Chronic Pain Begin? Scientists Close in on Its Origins

Researchers cataloged variations in RNA expression in the dorsal root ganglia cells of patients differing by pain state and sex. Using RNA sequencing, a specialized form of gene sequencing, on those DRG cells yielded a l...
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The Migraine Eye: Distinct Rod-Driven Retinal Pathways' Response to Dim Light Challenges the Visual Cortex Hyperexcitability Theory

Migraine-type photophobia, most commonly described as exacerbation of headache by light, affects nearly 90% of the patients. It is the most bothersome symptom accompanying an attack. Using subjective psychophysical asses...
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Assessment of the FDA Risk Evaluation and Mitigation Strategy for Transmucosal Immediate-Release Fentanyl Products

 Did the US Food and Drug Administration's (FDA's) Transmucosal Immediate-Release Fentanyl (TIRF) Risk Evaluation and Mitigation Strategy (REMS) meet its goal of preventing inappropriate use of TIRF products, such a...
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Opioid Use in the Family May Influence Adolescents’ Opioid Risk after Surgery

The presence of one or more family members using long-term opioids before a procedure was associated with a higher likelihood that adolescents prescribed opioids for the first time would do the same, according to the fin...
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How Young Adults Experience Pain Affects Self-Injury, Rutgers Study Finds

Teenagers and young adults who intentionally hurt themselves engage in such behavior based, in part, on how they experience pain and their emotional distress, according to a Rutgers study. The study, which examines physi...
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U.S. Opioid Deaths Jump Fourfold in 20 Years; Epidemic Shifts to Eastern States

The opioid epidemic is no longer concentrated among whites in Appalachian and Midwestern states, according to a new study from Stanford, Harvard and the University of Toronto.

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The AAPM Annual Meeting offers education and networking opportunities for all members of the pain care team.

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