This section will include pain research in the news, general stories about research and findings, pain abstracts in the news, and PubMed abstracts

Treatment Patterns and Medication Use in Patients with Postherpetic Neuralgia

Postherpetic neuralgia (PHN) is a chronic, painful condition characterized by persistent pain following resolution of a herpes zoster (HZ) infection. Epidemiologic data demonstrate that the risks for HZ infections and the development of PHN increase with age.

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Are Perioperative Interventions Effective in Preventing Chronic Pain After Primary Total Knee Replacement? A Systematic Review

For many people with advanced osteoarthritis, total knee replacement (TKR) is an effective treatment for relieving pain and improving function. Features of perioperative care may be associated with the adverse event of c...
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Tonic Suppression of the Mesolimbic Dopaminergic System by Enhanced Corticotropin-Releasing Factor Signaling Within the Bed Nucleus of the Stria Terminalis in Chronic Pain Model Rats

Although dysfunction of the mesolimbic dopaminergic system has been implicated in chronic pain, the underlying mechanisms remain to be elucidated. We hypothesized that increased inhibitory inputs to the neuronal pathway ...
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Spinal Cord Stimulation Failure: Evaluation of Factors Underlying Hardware Explantation

Spinal cord stimulation has been shown to improve pain relief and reduce narcotic analgesic use in cases of complex refractory pain syndromes. However, a subset of patients ultimately undergoes removal of the spinal cord...
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Self-Motion Perception Is Sensitized in Vestibular Migraine: Pathophysiologic and Clinical Implications

Vestibular migraine (VM) is the most common cause of spontaneous vertigo but remains poorly understood. We investigated the hypothesis that central vestibular pathways are sensitized in VM by measuring self-motion percep...
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Innovative Addiction Treatments Hold Promise for Stemming the Opioid Crisis

In a report published in Psychological Science in the Public Interest , scientists in health behavior, neuroscience, pain management, and addiction describe advances in brain science that can explain an individual's vuln...
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Physical Therapy Access May Reduce Opioid Prescriptions

Now, a new School of Public Health study finds that patients who first saw a primary care physician (PCP) for low back pain were 79 percent more likely to use prescription opioids than patients who first went to a chirop...
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Medical Device Safety in the Real World: Tapping EHR Data

Before any medical device reaches the market, it has to meet certain safety standards set by the Food and Drug Administration. But these standards are just a first step -- any number of things can happen when the devices hit the clinic.

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FDA

Inflammation Amps Up Neurite Growth, Gene Expression Involved in Heat, Cold Sensitivity

Researchers from North Carolina State University have found that inflammation increases neuronal activity, gene expression and sensory nerve (neurite) outgrowth in neurons involved in thermal – but not physical– sensatio...
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Treatment for Chronic Neuropathic Pain Gets to Brain via Novel Route

The new, minimally invasive procedure developed by University at Buffalo researchers utilizes delivery of an antibody that targets and thus blocks the pro-inflammatory protein called tumor necrosis factor-alpha (TNF), sp...
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The AAPM Annual Meeting offers education and networking opportunities for all members of the pain care team.

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