NIH Clinical Trials, open periods for grants, etc.

Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study (GREAT1)

This is a prospective, descriptive, observational research study designed to observe and document the clinical practice by domain experts, and how the knowledge of new findings that are published in the medical literatur...
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Impact of a Yoga Intervention on Pain and Multiomics in Participants With IBS

The purpose of this research study is to see if a six-week yoga program reduces abdominal pain in people with irritable bowel syndrome (IBS). This study also looks at whether the yoga program changes the composition of m...
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Objective Pain Measurement Using a Wearable Biosensor and a Mobile Platform in Patients With Endometriosis

This study aims to explore a novel objective measurement for endometriosis-related pain. A variety of pain symptoms are associated with endometriosis, including dysmenorrhea, dyspareunia, dysuria, dyschezia and chronic p...
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A Behavioral Intervention for Depression and Chronic Pain in Primary Care

Chronic pain and depression frequently co-exist in late and mid-life and contribute to increased disability, high health care costs, psychiatric comorbidity, and suicide. Older and middle-aged depressed-pain patients: a)...
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Noninvasive Brain Stimulation for Pain Relief

Non-invasive brain stimulation techniques, transcranial magnetic stimulation (TMS) and transcranial focused ultrasound (FUS), is be applied to healthy human subjects, acute pain patients, and chronic pain patients to inv...
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Pilot Testing an Intervention to Facilitate Tapering in Primary Care

This study proposes to pilot test an intervention to facilitate opioid pain reliever (OPR) tapering in primary care. The intervention will incorporate a clinician embedded within primary care to follow tapering dose sche...
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Virtual Reality for the Treatment of Chronic Low Back Pain

Chronic low back pain is highly prevalent in US adults and is a major cause of missed work days and disability. While several treatment options exist, chronic opioids are commonly used for these conditions even though there are limited data supporting efficacy, and clear evidence of harm associated with chronic opioid administration. 

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Lower Back Biomechanics in Veterans with Non-Specific Low Back Pain

Low back pain (LBP) is strongly associated with opioid consumption among Veterans, and improved clinical management of LBP is likely to reduce reliance on opioid among Veterans. Up to 60% of patients with an acute episod...
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Scrambler Therapy for the Reduction of Chemotherapy-Induced Neuropathic Pain

This trial studies how well scrambler therapy works in reducing chemotherapy-induced neuropathic pain in patients with cancer. Scrambler therapy is a type of treatment that uses electrodes placed on the skin. Electricity...
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Persistent Post-Mastectomy Pain: Randomized Clinical Trial of Targeted Pain Coping Skills Training

The purpose of this study is to test a skills training program to help with coping skills for pain that was designed specifically for women with persistent pain after breast cancer surgery.

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