NIH Clinical Trials, open periods for grants, etc.

Mechanisms of Change in Adolescent Pain Self-Management

Brief Summary: The MOCAS Study aims to describe the mechanisms through which sleep deficiency affects youth responses to an online pain self-management intervention over a 6-month period. The study is a single arm trial ...
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Mind Body Therapy for the Treatment of Chronic Pain

 Brief Summary: The goal of this study is to determine if mind body therapies can help people suffering from chronic back pain. The study is a randomized, partially blinded trial examining the effectiveness of mind body interventions (treatment arms) in reducing disability from back pain and alleviating back pain in participants as compared to usual care (control arm ). The investigators will secondarily investigate whether mind body interventions improve participant quality of life and reduce the need for pain-related hospitalization.

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Multimodal Analgesia With NSAID vs. Narcotics Alone After Shoulder Instability Surgery

This will be a single-center, prospective observational study. The study will compare post- operative pain scores and narcotic consumption between two groups of patients - one cohort will receive ibuprofen (Motrin) and P...
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Self-Administered Transcranial Direct Current Stimulation for Pain in Older Adults With Knee Osteoarthritis: A Phase II Randomized Sham-Controlled Trial

The purpose of this study is to assess the feasibility, acceptability, and efficacy of self-administered transcranial direct current stimulation (tDCS) in older adults with knee osteoarthritis (OA).

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Evaluation of NMES for Reducing Pain and Improving Functional Outcomes in Knee OA Patients (NMES)

Study Description: Brief Summary: The present prospective trial is designed to evaluate the efficacy of CyMedica Orthopedics e-viveā„¢ system, a multifunctional electrotherapy device providing neuromuscular electrical stim...
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Mindfulness-based Dance/Movement Therapy for Chronic Low Back Pain

 Study Description: Brief Summary: The purpose of this study is to evaluate the feasibility, acceptability and credibility of a mindfulness-based dance/movement therapy(M-DMT)protocol; to assess and improve methodol...
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Functional Spectroscopy Mapping of Pain Processing Cortical Areas During Non-Painful Peripheral Electrical Stimulation of the Accessory Spinal Nerve

Peripheral electrical stimulation (PES), which encompasses several techniques with heterogeneous physiological responses, has shown in some cases remarkable outcomes for pain treatment and clinical rehabilitation. Howeve...
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Comparison of Movement Pattern Training and Manual Therapy for Prearthritic Hip Disorders

Study Description: Brief Summary: Specific Aims Significance: Intra-articular, prearthritic hip disorders (PAHD) result in substantial dysfunction in young adults and are proposed precursors to hip osteoarthritis (OA). Our long term goal is to develop effective treatment strategies for people with PAHD that will improve function, decrease pain and prevent or delay the onset of OA. The purpose of this study is to compare movement pattern training (MoveTrain) and manual therapy (ManTher) in their effect on post-treatment, patient-reported outcomes and targeted impairments thought to contribute to PAHD.

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Phenol Neurolysis of Genicular Nerves for Chronic Knee Pain

Study Description: Brief Summary: Chronic knee pain from osteoarthritis (OA) is commonly treated with total knee arthroplasty (TKA) when conservative therapies fail to provide pain relief. More than 600,000 TKAs are performed in the U.S. annually, a number that continues to increase. A logistic-regression model suggests that the incidence rate of TKA will increase by 143% in the United States by 2050 compared to 2012. Although TKA is successful in reducing knee pain and joint stiffness in most cases, it can be associated with a 7-35% incidence of persistent refractory post-surgical knee pain.

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Human Translingual Neurostimulation Alters Resting Brain Activity in High-Density EEG

 Abstract: Background: Despite growing evidence of a critical link between neuromodulation technologies and neuroplastic recovery, the underlying mechanisms of these technologies remain elusive. Read the details. &n...
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