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Source: Journal of Neuroscience Abstract: Pain associates both sensory and emotional aversive components, and often leads to anxiety and depression when it becomes chronic. Here, we characterized, in a mouse model, the long-term development of [...]

Source: University of Granada A pioneering international study, carried out by the University of Granada, Harvard University, the University of California, Los Angeles (UCLA), the University of Florida, Laval University and the Jackson Laboratory has [...]

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Source: Oregon Health & Science University New research published in the journal Nature for the first time reveals the atomic structure of a key molecular component of the nervous system. Scientists at OHSU used advanced [...]

Source: Cochrane Bottom line: There is a lack of good evidence that any cannabis-derived product works for any chronic neuropathic pain. Background: Neuropathic pain is pain coming from damaged nerves. It is different from pain [...]

Source: Nature Communications Abstract: Peripheral neuropathic pain (PNP) is a debilitating and intractable chronic disease, for which sensitization of somatosensory neurons present in dorsal root ganglia that project to the dorsal spinal cord is a [...]

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Source: Johns Hopkins Medicine Using computer models and laboratory rats, Johns Hopkins researchers have demonstrated that "direct electrical current" can be delivered to nerves preferentially, blocking pain signals while leaving other sensations undisturbed.Full story...

Source: Nature Communications Abstract: Mechanical allodynia is a major symptom of neuropathic pain whereby innocuous touch evokes severe pain. Here we identify a population of peripheral sensory neurons expressing TrkB that are both necessary and [...]