Changing Dynamics of the Drug Overdose Epidemic in the United States from 1979 Through 2016

Source: PubMed.gov Read the abstract .

Scientists Take Big Step Toward Finding Non-Addictive Pain Killer

Source: Wake Forest Baptist Medical Center Scientists at Wake Forest School of Medicine have been working to find a safe, non-addictive pain killer. Known as AT-121, the new chemical compound has dual therapeutic action ...
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BIDMC Study Determines Risk Factors for Opioid Misuse

Source: Beth Israel Deaconess Medical Center Researchers and clinicians at Beth Israel Deaconess Medical Center (BIDMC) have performed the first meta-analysis to pool the effects of risk factors that place patients at an...
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Integrating Treatment at the Intersection of Opioid Use Disorder and Infectious Disease Epidemics in Medical Settings: A Call for Action After a National Academies of Sciences, Engineering, and Medicine Workshop

Source: Annals of Internal Medicine Abstract: As a result of the opioid use disorder (OUD) epidemic (1), new epidemics of hepatitis C virus (HCV) and HIV infection have arisen and hospitalizations for bacteremia, endocar...
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Opioid Epidemic Responses Overlook Gender

Source: Yale University In a commentary published in The Lancet , Women's Health Research at Yale Director Carolyn M. Mazure, and Yale Program in Addiction Medicine Director David A. Fiellin, M.D., called for researchers...
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The Effect of Incomplete Death Certificates on Estimates of Unintentional Opioid-Related Overdose Deaths in the United States, 1999-2015

Source: Public Health Reports Abstract: Objectives: A complete and accurate count of the number of opioid-related overdose deaths is essential to properly allocate resources. We determined the rate of unintentional overd...
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Rutgers Co-Author Available for Interviews on Study Showing High Risk of Dying Among Survivors of Opioid Overdoses

Source: Rutgers University-New Brunswick Rutgers Professor Stephen Crystal, who co-authored a pioneering study showing that U.S. survivors of opioid overdoses are highly likely to die within a year from drug use–related ...
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Overdose Risk Quintuples with Opioid and Benzodiazepine Use

Source: Health Sciences at the University of Pittsburgh In the first 90 days of concurrent opioid and benzodiazepine use, the risk of opioid-related overdose increases five-fold compared to opioid-only use among Medicare...
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Medication for Opioid Use Disorder After Nonfatal Opioid Overdose and Association with Mortality: A Cohort Study

Source: Annals of Internal Medicine Abstract: Background: Opioid overdose survivors have an increased risk for death. Whether use of medications for opioid use disorder (MOUD) after overdose is associated with mortality ...
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Potentially Inappropriate Opioid Prescribing, Overdose, and Mortality in Massachusetts, 2011–2015

Source: Journal of General Internal Medicine Abstract: Background: Potentially inappropriate prescribing (PIP) may contribute to opioid overdose. Key Results: All six types of PIP were associated with higher adjusted haz...
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Effect of Restricting the Legal Supply of Prescription Opioids on Buying Through Online Illicit Marketplaces: Interrupted Time Series Analysis

Source: BMJ Abstract: Objective: To examine the effect on the trade in opioids through online illicit markets ("cryptomarkets") of the US Drug Enforcement Administration's ruling in 2014 to reschedule hydrocodone combina...
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The Burden of Opioid-Related Mortality in the United States

Source: JAMA Abstract: Importance: Opioid prescribing and overdose are leading public health problems in North America, yet the precise public health burden has not been quantified. Conclusions and Relevance: Premature d...
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Four Factors Predict Chronic Opioid Use, Suggests Study by WVU Researchers

Source: West Virginia University Four factors increase the odds that a patient will wind up on chronic opioid therapy, suggests research conducted by a team of researchers led by Nilanjana Dwibedi, assistant professor in...
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Association Between Prescription Drug Monitoring Programs and Nonfatal and Fatal Drug Overdoses: A Systematic Review

Source: Annals of Internal Medicine Abstract: Background: Prescription drug monitoring programs (PDMPs) are a key component of the president's Prescription Drug Abuse Prevention Plan to prevent opioid overdoses in the Un...
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College Education Linked to Opioid Misuse among Baby Boomers

Source: University of Buffalo The more educated a member of the baby boomer generation, the more likely they are to misuse prescription opioids, according to new research from the University at Buffalo. Full story...

IU Research Suggests Failed Osteoarthritis Drug Could Get New Life as Opioid-Addiction Treatment

Source: Indiana University A new study from Indiana University suggests that a drug proven safe for use in people may prevent opioid tolerance and physical dependence when used in combination with opioid-based pain medic...
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Opioid Abuse Leads to Heroin Use and a Hepatitis C Epidemic, USC Researcher Says

Source: University of Southern California Heroin is worse than other drugs because people inject it much sooner, potentially resulting in increased risk of injection-related epidemics such as hepatitis C and HIV, a Keck ...
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In the Opioid Crisis, Military Research May Protect Citizens and Warfighters

Source: Armed with Science DOD Blog Ten thousand times more potent than morphine, the drug carfentanil poses a risk to both civilians and warfighters. The powerful opioid, with lethal amounts smaller than a poppy seed, w...
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A Qualitative Analysis of Gabapentin Misuse and Diversion Among People Who Use Drugs in Appalachian Kentucky

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Surgery Patients in Enhanced Recovery Program Leave Hospital Sooner, Take Fewer Opioids

Source: American Society of Anesthesiologists Colorectal and bariatric surgery patients benefited from an enhanced recovery after surgery (ERAS) program, leaving the hospital sooner and requiring fewer opioids to control...
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Tamper-Resistant Opioids No Panacea for Opioid Crisis

Source: Medscape Full story (login required)... View abstract in Lancet Psychiatry ...  

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