Penn’s ‘Enhanced Recovery’ Protocol Reduces Opioid Use in Spinal Surgery Patients

A new study published in the Journal of Neurosurgery: Spine showed that when an ERAS protocol was employed—which optimizes patients' surgical care before, during, and after surgery, including patient education, post-operative medications, and recovery plans—fewer patients needed pain medications one month after surgery. Full story
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Training the Prescriber: An Institutional Effort to Reduce the Amount of Opioids Prescribed Following Lumbar Surgery

A new study shows that an educational program on opiate use and misuse, the role of the orthopedic prescriber, multimodal analgesia, and state laws regarding opioid prescription could change prescriber behavior and result in a lower amount of prescribed opioids after lumbar surgery. Full story .
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Microglia Promote Increased Pain Behavior Through Enhanced Inflammation in the Spinal Cord During Repeated Social Defeat Stress

Clinical studies indicate that psychosocial stress contributes to adverse chronic pain outcomes in patients, but it is unclear how this is initiated or amplified by stress. Read the abstract . 
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Multisociety Research Collaboration—Small Research Group Update

The Multisociety Research Collaboration (MRC) provides a forum for specialty societies to identify critical gaps in the evidence base where additional high-quality research is needed to clarify the role of interventional pain procedures in the treatment of patients with spine conditions. In a recent project, MRC participants identified lumbar trans...
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Burst Spinal Cord Stimulation (Burst-SCS) Study (NCT03718325)

Source: ClinicalTrials.gov Read the details .
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Spine Pain Intervention to Enhance Care Quality And Reduce Expenditure (SPINE CARE)

Source: ClinicalTrials.gov Read more...
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Coverage of Nonpharmacologic Treatments for Low Back Pain Among US Public and Private Insurers

Source: JAMA Network Open Read the abstract . 
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Mesenchymal Stem Cells for Lumbar Degenerative Disc Disease (NCT03692221)

Source: ClinicalTrials.gov Read the details . 
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Genome-Wide Meta-Analysis of 158,000 Individuals of European Ancestry Identifies Three Loci Associated with Chronic Back Pain

Source: PLOS Genetics Read the abstract . 
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Comparing Long-term Effectiveness of High Frequency and Burst Spinal Cord Stimulation (NCT03681262)

Source: ClinicalTrials.gov Read the details .
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Video Game-Based Exercises for Older People with Chronic Low Back Pain: A Randomized Controlled Trial (GAMEBACK)

Source: Physical Therapy Read the abstract .
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After Doctors Cut Their Opioids, Patients Turn to a Risky Treatment for Back Pain

Source: The New York Times As physicians look to decrease the use of opioids, the use of anti-inflammatory injections for back and neck conditions are gaining popularity. AAPM President Jianguo Cheng, MD PhD, submitted a letter to the editor for possible publication in response to this article, pointing out that the negative characterization of int...
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Spinal Manipulation and Exercise for Low Back Pain in Adolescents: A Randomized Trial

Source: PubMed.gov Read more...
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Transcranial DCS May Boost Mood in Chronic Low Back Pain

Source: Medscape Full story (login required)...  
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D-cycloserine for the Treatment of Chronic, Refractory Low Back Pain

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Health Care Utilization and Overall Costs Based on Opioid Dependence in Patients Undergoing Surgery for Degenerative Spondylolisthesis

Source: PubMed.gov Read more...  
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Osteopathic Manipulative Treatment including Specific Diaphragm Techniques Improves Pain and Disability in Chronic Non-Specific Low Back Pain: A Randomized Trial

Source: PubMed.gov Read more...
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Clinical Practice Guidelines for Neck and Low Back Pain in Outpatient Physical Therapy

Source: ClinicalTrials.gov Read more...
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Vertebroplasty Versus Sham Procedure for Painful Acute Osteoporotic Vertebral Compression Fractures (VERTOS IV): Randomised Sham Controlled Clinical Trial

Source: BMJ Abstract: Objective: To assess whether percutaneous vertebroplasty results in more pain relief than a sham procedure in patients with acute osteoporotic compression fractures of the vertebral body. Conclusions: Percutaneous vertebroplasty did not result in statistically significantly greater pain relief than a sham procedure during 12 m...
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Selecting Effective Combinations of Treatment for Low Back Pain (SELECT LBP)

Source: ClinicalTrials.gov Read more...
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Back Pain Treatment Costs, Opioid Use Drop When Patients Seek Immediate Care

Source: University of Central Florida A research team led by the University of Central Florida has evaluated how the use of physical therapy to treat acute low back pain ― and the timing of when treatment begins ― impact the use and costs of health care. The researchers found that patients who started physical therapy within three days of receiving...
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CÚRAM Researchers Find Potential New Treatment for Lower Back Pain

Source: NUI Galway, Ireland Professor Abhay Pandit and his research team at CÚRAM, the SFI Research Centre for Medical Devices based at NUI Galway, have just published their research into a potential new treatment for lower back pain in the prestigious journal Science Advances . The research team developed a biomaterial-based therapy that can be ad...
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Low-Cost Tool for Compliance and Treatment-Tracking of Low Back Pain Patients

Source: ClinicalTrials.gov Read more...  
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The Lancet Series on Low Back Pain

Source: The Lancet The Lancet publishes three papers on low back pain, by an international group of authors led by Prof Rachelle Buchbinder, Monash University, Melbourne, Australia, which address the issues around the disorder and call for worldwide recognition of the disability associated with the disorder and the removal of harmful practices. Rea...
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Spinal and Supra-Spinal Pain Mechanisms in Patients with Fibromyalgia

Source: ClinicalTrials.gov Read more...
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The VIGOR Study - Virtual Immersive Gaming to Optimize Recovery in Low Back Pain (VIGOR)

Source: ClinicalTrials.gov Read more...  
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Pain Relief Now, More Pain Later? Early Use of Opioids Worsens Pain Down the Road for Spinal Cord Injury Patients

Source: Association of Academic Physiatrists A new study presented this week at the Association of Academic Physiatrists Annual Meeting in Atlanta found that opioids prescribed to patients soon after an acute traumatic spinal cord injury is associated to increased pain just one year later. Full story...  
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Eplerenone as a Supplement to Epidural Steroid Injections

Source: ClinicalTrials.gov Read more...  
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Predicting Drug Efficacy in Chronic Low Back Pain by Quantitative Sensory Tests

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University of Michigan/Wayne State Chronic Pain Study

Source: ClinicalTrials.gov Read more...  
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