Long-Term Safety and Efficacy of Closed-Loop Spinal Cord Stimulation to Treat Chronic Back and Leg Pain (Evoke): A Double-Blind, Randomised, Controlled Trial.

Summary: Background: Spinal cord stimulation has been an established treatment for chronic back and leg pain for more than 50 years; however, outcomes are variable and unpredictable, and objective evidence of the mechani...
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Identification of Spinal Afferent Nerve Endings in the Colonic Mucosa and Submucosa That Communicate Directly With the Spinal Cord: The Gut-Brain Axis.

  Abstract:  The major sensory nerve pathway between the colon and central nervous system (spinal cord and brain) that underlies the gut-brain axis, is via spinal afferent neurons, with cell bodies in dorsal ro...
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Patient Experience Comparing Tonic Vs. Burst Spinal Cord Stimulation For Chronic Pain

Researchers are evaluating if subjects who have already experienced tonic spinal cord stimulation would have a better pain relief status with burst spinal cord stimulation. Read the details .

Spinal Cord Stimulation Failure: Evaluation of Factors Underlying Hardware Explantation

Spinal cord stimulation has been shown to improve pain relief and reduce narcotic analgesic use in cases of complex refractory pain syndromes. However, a subset of patients ultimately undergoes removal of the spinal cord...
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FDA Approves Abbott's "Low Dose," Recharge-Free Spinal Cord Stimulation System with up to Ten Year Battery Life for People Living with Chronic Pain

Abbott (NYSE: ABT) today announced the U.S. Food and Drug Administration (FDA) has approved the company's Proclaim XR™ recharge-free neurostimulation system for people living with chronic pain. The Proclaim XR platform o...
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In Lab, SLU Researchers Flip Pain Switch in Spinal Cord Cells

Facing an urgent need for safer and more effective therapies for those suffering from debilitating pain, Saint Louis University researchers are on a mission to find a non-narcotic off-switch for pain.  Full story. &...
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