ASA, AAOS Launch Toolkit to Help Physicians Safely, Effectively Alleviate Patients’ Postoperative Pain with Reduced Opioid Use

The toolkit provides physicians and patients with resources to encourage communication and decision-making to help reduce patients' postoperative pain as much and as safely as possible.

Continue reading

IL-4 Induces M2 Macrophages to Produce Sustained Analgesia Via Opioids

IL-4 is a pleiotropic antiinflammatory cytokine, which can be neuroprotective after nervous system injury. The beneficial actions of IL-4 are thought to result from the blunting of action of inflammatory mediators, such ...
Continue reading
Topics:

Association of Opioid Use with Pain and Satisfaction After Dental Extraction

Dentists commonly prescribe opioids to relieve pain after tooth extraction. Understanding the differences in patient-reported outcomes between opioid users and nonusers could encourage the adoption of more conservative a...
Continue reading
Topics:

AAPM Member Discusses Challenges of Treating Chronic Pain Patients Amidst Opioid Crisis

"We're de-prescribing without having sufficient evidence on how to do this the right way, how to protect patients," says AAPM member, Beth Darnall, PhD , in a recent Guardian Australia interview. Full story .

Intermountain Healthcare First Health System in Utah to Offer Formal Opioid-Free Surgery Program for Patients Wanting Alternative Pain Control Options

The new program was tested for three months as part of a pilot project, in which physicians utilized non-addictive and less-addictive pain management alternatives for surgical patients looking for alternative pain contro...
Continue reading

Associations Between Stopping Prescriptions for Opioids, Length of Opioid Treatment, and Overdose or Suicide Deaths in US Veterans: Observational Evaluation

The objective of this study is to examine the associations between stopping treatment with opioids, length of treatment, and death from overdose or suicide in the Veterans Health Administration.  Read the abstract ....
Continue reading

3D Printed Opioid Medicines with Alcohol-Resistant and Abuse-Deterrent Properties

In the past decade, prescriptions for opioid medicines have been exponentially increasing, instigating opioid abuse as a global health crisis associated with high morbidity and mortality. Read the abstract . 
Topics:

Hormone Linked to Pain Difference Between Men and Women

Researchers identified a mechanism that explains why women may be more vulnerable than men to develop pain in general, as well as to develop pain from opioids specifically. The cause is a neurohormone, prolactin, known l...
Continue reading
Topics:

Psychologist Uses Computer-Simulated Patients to Untangle Sociological Influences in Pain Care

In a recent study published in the journal Pain , researchers found that white physicians who self-scored higher on "intergroup anxiety" -- discomfort during interactions with groups who share fewer similar characteristi...
Continue reading

Surgeons in a Large Health-Care System Cut Opioid Prescriptions of Five or More Days by 64 Percent Using a New Multipronged Program

Physician education, monitoring, and incentives lead to a shift from longer-term to shorter-term prescriptions for surgical patients, according to new Journal of the American College of Surgeons study. Full story .
Topics:

Pilot Testing an Intervention to Facilitate Tapering in Primary Care

This study proposes to pilot test an intervention to facilitate opioid pain reliever (OPR) tapering in primary care. The intervention will incorporate a clinician embedded within primary care to follow tapering dose sche...
Continue reading

Virtual Reality for the Treatment of Chronic Low Back Pain

Chronic low back pain is highly prevalent in US adults and is a major cause of missed work days and disability. While several treatment options exist, chronic opioids are commonly used for these conditions even though there are limited data supporting efficacy, and clear evidence of harm associated with chronic opioid administration. 

Continue reading

University of Iowa Professor’s Opioid Research Evaluates Link Between Opioid Use and Chronic Pain

AAPM member and University of Iowa researcher, Barbara St. Marie PhD, RN , recently conducted NIDA-funded research on opioid misuse and substance abuse disorders to help clinicians treat patients for chronic pain. St. Ma...
Continue reading

U.S. Surgeon General to Deliver AAPM 2020 Keynote

The American Academy of Pain Medicine Program Committee is excited to announce that U.S. Surgeon General Vice Admiral Jerome M. Adams, MD MPH , will deliver a keynote address about the importance of pain management in co...
Continue reading

A Systematic Review of the Evidence for the Efficacy of Opioids for Chronic Non-Cancer Pain in Community-Dwelling Older Adults

The ageing global population and concomitant increase in the use of opioid analgesia have highlighted the need to evaluate the effectiveness of opioids for chronic pain in older people.

Continue reading

Preemptive Pain Management Program Is Associated with Reduction of Opioid Prescriptions After Benign Minimally Invasive Foregut Surgery

The opioid crisis is partly due to opioids prescribed after elective surgery. This study sought to determine if a preemptive pain-management program would be associated with opioid-free discharge after benign foregut surgery.

Continue reading

Nanoparticle Drug Delivery Could Offer More Effective Pain Relief Than Opioids

Findings from a recent study published in Nature Nanotechnology , showed that the nanoparticles were actually more effective than opioids in models of acute pain, chronic inflammatory pain, and neuropathic pain. Full sto...
Continue reading

Physician Office Visits at Which Benzodiazepines Were Prescribed: Findings From 2014–2016 National Ambulatory Medical Care Survey

The newly published report describes characteristics of visits to office-based physicians at which benzodiazepines were prescribed, including visits where opioids were coprescribed.

Continue reading
Topics:

Erector Spinae Plane Blocks (ESP) for Postoperative Pain in Lumbo-Sacral Spine Surgery

The goal of this study is to evaluate the analgesic efficacy of bilateral erector spinae plane (ESP) blocks after lumbar and lumbo-sacral spine surgery by assessing postoperative pain scores and opiate requirements as the primary outcome measures.

Continue reading
Topics:

Research Calls for New Measures to Treat Mental Illness and Opioid Use

Opioid use among psychiatric hospital patients needs to be addressed through an integrated approach to managing mental illness, pain and substance use, a study by researchers at the University of Waterloo has found. 

Continue reading

University of Maryland Center to Advance Chronic Pain Research Symposium

AAPM member Beth Hogans, MD PhD, served as a panelist on the University of Maryland Center to Advance Chronic Pain Research annual symposium, "Managing Chronic Pain Among Patients with Serious Illness During a National Opioid Crisis." 

Continue reading

Chronic Opioid Pretreatment Potentiates the Sensitization of Fear Learning by Trauma

Despite the large comorbidity between PTSD and opioid use disorders, as well as the common treatment of physical injuries resulting from trauma with opioids, the ability of opioid treatments to subsequently modify PTSD-related behavior has not been well studied.  

Continue reading
Topics:

Frequency of Cannabis and Illicit Opioid Use Among People Who Use Drugs and Report Chronic Pain: A Longitudinal Analysis

Ecological research suggests that increased access to cannabis may facilitate reductions in opioid use and harms, and medical cannabis patients describe the substitution of opioids with cannabis for pain management. Howe...
Continue reading

Trends in Gabapentin and Baclofen Exposures Reported to U.S. Poison Centers

Prescriptions for nonopioid pharmacological therapies such as gabapentin and baclofen have been increasing. While gabapentin and baclofen are less likely than opioids to result in fatal overdose, they are each associated with dependence, misuse and adverse effects.

Continue reading
Topics:

A New Link Between Migraines, Opioid Overuse May Be Key to Treating Pain

Researchers at the University of Illinois at Chicago and colleagues discovered that a peptide — small chains of amino acids that can regulate many behaviors and brain signaling pathways — links together migraine pain and...
Continue reading
Topics:

Fighting Opioids with an Unlikely Supplemental Painkiller: Anti-Itch Medicine

  A West Virginia University researcher is investigating whether an anti-itch medication that targets a specific part of our nerve cells can make morphine—which targets a different part—more effective.

Continue reading
Topics:

Selective Modulation of Tonic Aversive Qualities of Neuropathic Pain by Morphine in the Central Nucleus of the Amygdala Requires Endogenous Opioid Signaling in the Anterior Cingulate Cortex

The amygdala is a key subcortical region thought to contribute to emotional components of pain. As opioid receptors are found in both the central (CeA) and basolateral (BLA) nuclei of the amygdala, we investigated the ef...
Continue reading

Trends and Rapidity of Dose Tapering Among Patients Prescribed Long-Term Opioid Therapy, 2008-2017

How often are patients who are prescribed long-term opioids undergoing tapering of their daily doses, and how often do patients undergo a rapid taper rate? Read the abstract.
Topics:

DEA Announces Additional Regulatory Steps to Address Opioid Epidemic

The Drug Enforcement Administration announced proposed regulations to improve DEA's ability to oversee the production of dangerous drugs at the height of the national opioid crisis. This proposed regulation would further...
Continue reading
Topics:

Innovative Addiction Treatments Hold Promise for Stemming the Opioid Crisis

In a report published in Psychological Science in the Public Interest , scientists in health behavior, neuroscience, pain management, and addiction describe advances in brain science that can explain an individual's vuln...
Continue reading
Topics:

Anxiety Among Patient Factors Linked to More Opioid Use After Surgery

New research from Michigan Medicine could help clinicians identify which patients are more likely to continue to use opioids after surgery recovery.

Continue reading

Trump Administration Announces $1.8 Billion in Funding to States to Continue Combating Opioid Crisis

The U.S. Department of Health and Human Services (HHS) announced more than $1.8 billion in funding to states to continue the Trump administration's efforts to combat the opioid crisis by expanding access to treatment and supporting near real-time data on the drug overdose crisis.

Continue reading
Topics:

Mortality After Discontinuation of Primary Care–Based Chronic Opioid Therapy for Pain: A Retrospective Cohort Study

 Despite known risks of using chronic opioid therapy (COT) for pain, the risks of discontinuation of COT are largely uncharacterized. The objective of this study was to evaluate mortality, prescription opioid use, and primary care utilization of patients discontinued from COT, compared with patients maintained on opioids.

Continue reading
Topics:

6 Key Steps that States Should Take Now to End the Opioid Epidemic

The AMA has released a national policy road map based on in-depth analysis of the response to the opioid epidemic by four states: Colorado, Mississippi, North Carolina and Pennsylvania. The report , " National Roadmap on...
Continue reading
Topics:

Mixing Marijuana with Opioids May Not Be Good for Mental Health

AAPM Secretary W. Michael Hooten, MD comments on a new study on opioid and cannabis co-use, pointing out that the study shows us "that individuals with chronic pain who use opioids and cannabis concurrently are more likely to have mental health problems and other substance use issues, and that is very important." Dr. Hooten was not an author in the study.

Continue reading

How To Teach Future Doctors About Pain in the Midst of the Opioid Crisis

AAPM member Beth B. Hogans, MD PhD comments in this NPR interview about the four-day course she helped create at Johns Hopkins for medical students about pain and pain management at the start of their medical education. 

Continue reading
Topics:

New Route to Designing Safer Pain Medications Discovered

A team at Scripps Research in Florida has discovered a biological system that manages cells' response to opioid drug exposure. The unexpected discovery offers new ideas for improving the safety of the one of the most eff...
Continue reading
Topics:

Prevalence and Risk Factors Associated With Long-Term Opioid Use After Injury Among Previously Opioid-Free Workers.

Using opioids for acute pain can lead to long-term use and associated morbidity and mortality. Injury has been documented as a gateway to long-term opioid use in some populations, but data are limited for injured workers.

Continue reading

Study Shows Safety Initiative Decreases Opioid Use in VA Patients with Little Impact on Pain Scores

New research published in Anesthesiology reports that after an Opioid Safety Initiative (OSI) was implemented at the Veterans Health Administration, patients undergoing knee replacement surgery were prescribed significan...
Continue reading

New Opioid Speeds Up Recovery Without Increasing Pain Sensitivity or Risk of Chronic Pain

A novel opioid developed by researchers at Tulane University and the Southeast Louisiana Veterans Health Care System is as strong as morphine but isn't addictive and causes fewer side effects, according to a new study published in the Journal of Neuroinflammation

Continue reading

Oregon Panel Drops Effort to Cut Opioids and Cover Chronic Pain

An Oregon committee has abandoned a controversial proposal that would have expanded treatment options for chronic pain patients under the Oregon Health Plan, but would have forced many to reduce dosages or discontinue pr...
Continue reading

Oregon Panel Drops Effort to Cut Opioids and Cover Chronic Pain

An Oregon committee has abandoned a controversial proposal that would have expanded treatment options for chronic pain patients under the Oregon Health Plan, but would have forced many to reduce dosages or discontinue prescription opioids. 

Continue reading

FDA Announces Public Meeting to Discuss Safety and Utility of Higher-Dose Opioid Analgesics

FDA is seeking public input on the clinical utility and safety concerns associated with the higher range of opioid analgesic dosing (both in terms of higher strength products and higher daily doses) in the outpatient set...
Continue reading
Topics:

AAPM Foundation Convenes Opioid Reduction Consensus Panel

Pain management experts and patient advocates met this past week to begin developing clear evidence-informed guidance for healthcare clinicians on the reduction or elimination of opioids, when appropriate, for ...
Continue reading

FDA Identifies Harm Reported From Sudden Discontinuation of Opioid Pain Medicines

The U.S. Food and Drug Administration (FDA) has received reports of serious harm in patients who are physically dependent on opioid pain medicines suddenly having these medicines discontinued or the dose rapidly decreased. These include serious withdrawal symptoms, uncontrolled pain, psychological distress, and suicide. 

Continue reading
Topics:

2019 AAPM Meeting Highlights from Medscape

Read articles about the latest pain research present at AAPM35 in Denver, March 6-10, 2019.

Continue reading

Trends and Patterns of Geographic Variation in Opioid Prescribing Practices by State, United States, 2006-2017

Importance : Risk of opioid use disorder, overdose, and death from prescription opioids increases as dosage, duration, and use of extended-release and long-acting formulations increase. States are well suited to respond ...
Continue reading
Topics:

Opiates Prescribing for Knee Arthroscopies and ACL Reconstruction (NCT03876743)

The purpose of the study is to determine if opiates are required to achieve adequate analgesia after knee arthroscopy and ACL reconstruction in outpatient surgery.  The investigators hypothesize that patients are fr...
Continue reading
Topics:

Managing Twin Crises in Chronic Pain and Prescription Opioids

AAPM Past President Sean Mackey, MD PhD, co-authored a BMJ editorial on how the national pain strategies are part of the solution in managing this twin crises. 

Continue reading

Assessment of the FDA Risk Evaluation and Mitigation Strategy for Transmucosal Immediate-Release Fentanyl Products

 Did the US Food and Drug Administration's (FDA's) Transmucosal Immediate-Release Fentanyl (TIRF) Risk Evaluation and Mitigation Strategy (REMS) meet its goal of preventing inappropriate use of TIRF products, such a...
Continue reading
Topics:

Want more pain resources? Check out our library of on-demand education, upcoming events, and more.

Learn More