Selective Modulation of Tonic Aversive Qualities of Neuropathic Pain by Morphine in the Central Nucleus of the Amygdala Requires Endogenous Opioid Signaling in the Anterior Cingulate Cortex

The amygdala is a key subcortical region thought to contribute to emotional components of pain. As opioid receptors are found in both the central (CeA) and basolateral (BLA) nuclei of the amygdala, we investigated the ef...
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Trends and Rapidity of Dose Tapering Among Patients Prescribed Long-Term Opioid Therapy, 2008-2017

How often are patients who are prescribed long-term opioids undergoing tapering of their daily doses, and how often do patients undergo a rapid taper rate? Read the abstract.
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Prevalence and Risk Factors Associated With Long-Term Opioid Use After Injury Among Previously Opioid-Free Workers.

Using opioids for acute pain can lead to long-term use and associated morbidity and mortality. Injury has been documented as a gateway to long-term opioid use in some populations, but data are limited for injured workers.

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Study Shows Safety Initiative Decreases Opioid Use in VA Patients with Little Impact on Pain Scores

New research published in Anesthesiology reports that after an Opioid Safety Initiative (OSI) was implemented at the Veterans Health Administration, patients undergoing knee replacement surgery were prescribed significan...
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New Opioid Speeds Up Recovery Without Increasing Pain Sensitivity or Risk of Chronic Pain

A novel opioid developed by researchers at Tulane University and the Southeast Louisiana Veterans Health Care System is as strong as morphine but isn't addictive and causes fewer side effects, according to a new study published in the Journal of Neuroinflammation

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