McGill Researchers End Decade-Long Search for Mechanical Pain Sensor

Researchers at McGill University have discovered that a protein found in the membrane of our sensory neurons are involved in our capacity to feel mechanical pain, laying the foundation for the development of powerful new...
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Quality Improvement in Dementia Care

The Dementia Management Quality Measurement Set was first developed and released in 2013 by the PCPI Foundation. Developed by an appointed multistakeholder technical expert panel (TEP), the 2013 Measurement Set was suppo...
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Magnetic Resonance Imaging of Neuroinflammation in Chronic Pain: A Role for Astrogliosis?

Non-invasive measures of neuroinflammatory processes in humans could substantially aid diagnosis and therapeutic development for many disorders, including chronic pain. Several proton Magnetic Resonance Spectroscopy (H-M...
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Perturbing the Activity of the Superior Temporal Gyrus During Pain Encoding Prevents the Exaggeration of Pain Memories: A Virtual Lesion Study Using Single-Pulse Transcranial Magnetic Stimulation

Past studies have shown that pain memories are often inaccurate, a phenomenon known as mnemonic pain bias. Pain memories are thought to play an important role on how future pain is felt. Recent evidence from our laborato...
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Neurofeedback Impact on Veterans With mTBI

This study will evaluate neurofeedback (NFB) training as a low risk, non-invasive, effective treatment for Veterans diagnosed with mild traumatic brain injury (mTBI) and experiencing chronic post-concussive symptoms (PCS...
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Long Term Efficacy of Neuronavigation Guided rTMS in Alleviating Gulf War Illness Related Headaches and Pain Symptoms

This study aims to look at the long term efficacy of using repetitive transcranial magnetic stimulation (rTMS) in relieving Gulf War Illness related headaches and pain. 

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Feasibility of Near-Infrared Spectroscopy to Measure Cortical Pain Pathway (Brain) Activation During Dry Needling

The benefit experienced by some patients when treated with dry needling,1 combined with the field-expedient nature of this intervention, make dry needling uniquely suited for the military healthcare environment. An impro...
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New Discovery: How Chronic Pain Changes Your Brain and Personality

Australian researchers have found that people with chronic pain experience physical alterations in their brain that likely leads to negative changes in their personality. The study discovered that people with chronic pai...
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Tonic Suppression of the Mesolimbic Dopaminergic System by Enhanced Corticotropin-Releasing Factor Signaling Within the Bed Nucleus of the Stria Terminalis in Chronic Pain Model Rats

Although dysfunction of the mesolimbic dopaminergic system has been implicated in chronic pain, the underlying mechanisms remain to be elucidated. We hypothesized that increased inhibitory inputs to the neuronal pathway ...
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Inflammation Amps Up Neurite Growth, Gene Expression Involved in Heat, Cold Sensitivity

Researchers from North Carolina State University have found that inflammation increases neuronal activity, gene expression and sensory nerve (neurite) outgrowth in neurons involved in thermal – but not physical– sensatio...
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Topics:

Pain Neurology

Abstract: Pain is often the initial complaint for which patients seek medical care presenting both a diagnostic and therapeutic challenge to the primary care provider. The appreciation of pain is not merely the result of...
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