Associations Between Gabapentinoids and Suicidal Behavior, Unintentional Overdoses, Injuries, Road Traffic Incidents, and Violent Crime: Population Based Cohort Study in Sweden

Abstract: OBJECTIVE: To examine associations between gabapentinoids and adverse outcomes related to coordination disturbances (head or body injuries, or both and road traffic incidents or offences), mental health (suicid...
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A Clinical Overview of Off-label Use of Gabapentinoid Drugs

The gabapentinoid drugs gabapentin and pregabalin were originally developed as antiseizure drugs but now are prescribed mainly for treatment of pain. For gabapentin, the only pain-related indication approved by the US Food and Drug Administration (FDA) is postherpetic neuralgia. For pregabalin, FDA-approved indications related to pain are limited to postherpetic neuralgia, neuropathic pain associated with diabetic neuropathy or spinal cord injury, and fibromyalgia.

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