Key Chronic Low Back Pain Outcomes Remain Stable Over Time

A Journal of General Internal Medicine article, provided some insight into why chronic low back pain may be difficult to treat. Data published from the PRECISION Pain Research Registry, which looked at 289 chronic low ba...
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Six Building Blocks: A Team-Based Approach to Improving Opioid Management in Primary Care

The Agency for Healthcare Research and Quality released a toolkit offering a structured team-based approach designed to support clinics as they independently implement effective, guideline-driven care for their patients ...
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A Behavioral Intervention for Depression and Chronic Pain in Primary Care

Chronic pain and depression frequently co-exist in late and mid-life and contribute to increased disability, high health care costs, psychiatric comorbidity, and suicide. Older and middle-aged depressed-pain patients: a)...
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Behavioral Activation and Behavioral Inhibition: An Examination of Function in Chronic Pain

The objective of the study was to examine the BIS-BAS model of chronic pain. This model posits that 2 neurophysiological systems-the behavioral inhibition system (BIS) sensitized to and activated by punishment cues and t...
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AAPM Member Discusses Challenges of Treating Chronic Pain Patients Amidst Opioid Crisis

"We're de-prescribing without having sufficient evidence on how to do this the right way, how to protect patients," says AAPM member, Beth Darnall, PhD , in a recent Guardian Australia interview. Full story .

AAPM Members Discuss Clinical Challenges to Opioid Tapering in MedPage Today

AAPM members Beth Darnall, PhD , and W. Michael Hooten, MD , contributed to this MedPage Today article, Clinical Challenge: Opioid Tapering—New trials look at ways to help chronic pain patients take fewer drugs. Full sto...
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Can Pain Management be Safely Optimized in Older Adults?

Managing chronic pain is a challenging task. Older adults (OAs) (>65 years) are the fastest growing segment of our population, and are substantially affected by chronic pain of various etiologies. Read the abstract .&...
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Let It Be: Mindful Acceptance Down-Regulates Pain and Negative Emotion

Mindfulness training ameliorates clinical and self-report measures of depression and chronic pain, but its use as an emotion regulation strategy—in individuals who do not meditate—remains understudied. Read the abstract ...
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Psychologist Uses Computer-Simulated Patients to Untangle Sociological Influences in Pain Care

In a recent study published in the journal Pain , researchers found that white physicians who self-scored higher on "intergroup anxiety" -- discomfort during interactions with groups who share fewer similar characteristi...
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FDA Accepts Regulatory Submission for Tanezumab, a Potential First-in-Class Treatment for Patients with Chronic Pain Due to Moderate-to-Severe Osteoarthritis

​ Read the full story . 
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Association of Tramadol Use with Risk of Hip Fracture

Several professional organizations have recommended tramadol as one of the first-line or second-line therapies for patients with chronic noncancer pain and its prescription has been increasing rapidly worldwide; however, the safety profile of tramadol, such as risk of fracture, remains unclear.

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AAPM Members Contribute to HuffPost Article: How to Talk to Your Doctor If You're Experiencing Chronic Pain

AAPM Members Sara Davin, PhD and David Edwards, MD PhD were interviewed by Huffington Post about why it can be difficult to identify chronic pain treatments that work and how persons experiencing pain can communicate mos...
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T'ai Chi for Chronic Low Back Pain in Older Adults: A Feasibility Trial

T'ai chi (TC) has been found effective for improving chronic low back pain. However, such studies did not include adults over 65 years of age. This study was designed to evaluate the feasibility and acceptability of TC in this population compared with Health Education and with Usual Care.

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Virtual Reality for the Treatment of Chronic Low Back Pain

Chronic low back pain is highly prevalent in US adults and is a major cause of missed work days and disability. While several treatment options exist, chronic opioids are commonly used for these conditions even though there are limited data supporting efficacy, and clear evidence of harm associated with chronic opioid administration. 

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University of Iowa Professor’s Opioid Research Evaluates Link Between Opioid Use and Chronic Pain

AAPM member and University of Iowa researcher, Barbara St. Marie PhD, RN , recently conducted NIDA-funded research on opioid misuse and substance abuse disorders to help clinicians treat patients for chronic pain. St. Ma...
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Magnetic Resonance Imaging of Neuroinflammation in Chronic Pain: A Role for Astrogliosis?

Non-invasive measures of neuroinflammatory processes in humans could substantially aid diagnosis and therapeutic development for many disorders, including chronic pain. Several proton Magnetic Resonance Spectroscopy (H-M...
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A Systematic Review of the Evidence for the Efficacy of Opioids for Chronic Non-Cancer Pain in Community-Dwelling Older Adults

The ageing global population and concomitant increase in the use of opioid analgesia have highlighted the need to evaluate the effectiveness of opioids for chronic pain in older people.

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CMS Finalizes Decision to Cover Acupuncture for Chronic Low Back Pain for Medicare Beneficiaries

Before this final National Coverage Determination (NCD) reconsideration, acupuncture was nationally non-covered by Medicare. CMS conducted evidence reviews and examined the coverage policies of private payers to inform i...
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Perturbing the Activity of the Superior Temporal Gyrus During Pain Encoding Prevents the Exaggeration of Pain Memories: A Virtual Lesion Study Using Single-Pulse Transcranial Magnetic Stimulation

Past studies have shown that pain memories are often inaccurate, a phenomenon known as mnemonic pain bias. Pain memories are thought to play an important role on how future pain is felt. Recent evidence from our laborato...
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New Hope to Reduce Bladder Pain

The latest research led by Flinders University has now identified a link between UTI and bladder pain – caused by the immune system's fight against the infection. The research suggests this could be a leading cause of ch...
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Pain Treatment Using Human Stem Cells a Success

Human stem cells and "pain-killing neurons" have successfully relieved chronic pain in mice. The breakthrough method may be tested on human patients suffering untreatable pain within five years. 

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Nanoparticle Drug Delivery Could Offer More Effective Pain Relief Than Opioids

Findings from a recent study published in Nature Nanotechnology , showed that the nanoparticles were actually more effective than opioids in models of acute pain, chronic inflammatory pain, and neuropathic pain. Full sto...
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A User-Centered Approach to an Evidence-Based Electronic Health Pain Management Intervention for People With Chronic Pain: Design and Development of EPIO

Chronic pain conditions are complicated and challenging to live with. Electronic health (eHealth) interventions show promise in helping people cope with chronic illness, including pain. The success of these interventions...
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Management of Patients with a Musculoskeletal Pain Condition that Is Likely Chronic: Results from a National Cross-Sectional Survey

The purpose of the study was to explore clinical management for new cases of musculoskeletal pain that are likely chronic.  

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Management of Chronic Pain and PTSD in Gulf War Veterans With tDCS+Prolonged Exposure

Gulf War Veterans (a DoD/VA defined service era corresponding to the first Gulf War under operations Desert Storm and Desert Shield 1990-1991), especially those who present with Post-Traumatic Stress Disorder (PTSD), are...
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A Placebo for Pain Relief—Even When You Know It’s Not Real

Some patients with chronic pain can get relief from a placebo even when they know it isn't an active medication, a growing body of evidence shows. 

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Scientists Target Link Between Chronic Pain, Cognitive Impairments

Researchers at The University of Texas at Dallas have pinpointed a single biochemical pathway as a target for addressing both this neuropathic pain and the accompanying cognitive problems.

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Researchers Explore A Drug-Free Idea to Relieve Chronic Pain: Green Light

A small but growing body of research suggesting a link between green light and pain, including animal research. While there are not yet robust data on humans, some researchers see promise for a drug-free approach that co...
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Poor Sleep Worsens Recovery from Chronic Low Back Pain

Sleep problems may decrease the likelihood of recovery from chronic low back pain over the long term and those who have musculoskeletal pain on top of insomnia have an even lower possibility of recovery, according to the...
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Identifying Type of Chronic Pain in Adults with Sickle Cell Disease May Lead to Better Outcomes

Identifying the type of pain an adult with sickle cell disease experiences may be useful in improving treatment, according to a new study by researchers at Yale Cancer Center and Smilow Cancer Hospital. 

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Study Supports Long-Term Benefits of Non-Drug Therapies for Pain

A new study finds that non-drug therapies given to service members with chronic pain may reduce the risk of long-term adverse outcomes, such as alcohol and drug disorder and self-induced injuries, including suicide attempts.

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University of Maryland Center to Advance Chronic Pain Research Symposium

AAPM member Beth Hogans, MD PhD, served as a panelist on the University of Maryland Center to Advance Chronic Pain Research annual symposium, "Managing Chronic Pain Among Patients with Serious Illness During a National Opioid Crisis." 

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A MAPP Network Case-Control Study of Urological Chronic Pelvic Pain Compared with Nonurological Pain Conditions

Limited research suggests commonalities between urological chronic pelvic pain syndromes (UCPPS) and other nonurological chronic overlapping pain conditions (COPCs) including fibromyalgia, chronic fatigue syndrome, and i...
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Comparative Effectiveness of an Interdisciplinary Pain Program for Chronic Low Back Pain, Compared to Physical Therapy Alone

The aim of this study was to compare the effectiveness of PT to an interdisciplinary treatment approach in patients with chronic low back pain (CLBP).

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Frequency of Cannabis and Illicit Opioid Use Among People Who Use Drugs and Report Chronic Pain: A Longitudinal Analysis

Ecological research suggests that increased access to cannabis may facilitate reductions in opioid use and harms, and medical cannabis patients describe the substitution of opioids with cannabis for pain management. Howe...
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Yoga and Physical Therapy as Treatment for Chronic Lower Back Pain also Improves Sleep

Yoga and physical therapy (PT) are effective approaches to treating co-occurring sleep disturbance and back pain while reducing the need for medication, according to a new study. The research showed significant improveme...
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New Discovery: How Chronic Pain Changes Your Brain and Personality

Australian researchers have found that people with chronic pain experience physical alterations in their brain that likely leads to negative changes in their personality. The study discovered that people with chronic pai...
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Patient Experience Comparing Tonic Vs. Burst Spinal Cord Stimulation For Chronic Pain

Researchers are evaluating if subjects who have already experienced tonic spinal cord stimulation would have a better pain relief status with burst spinal cord stimulation. Read the details .

Immersion in Virtual Reality Scenes of the Arctic Helps to Ease People’s Pain

Watching immersive 360 videos of icy Arctic scenes helps to relieve burning pain and could hold hope for treating chronic pain, a study has found.  

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Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain

 Brief Summary:Chronic pain affects 1 in 4 US adults, and many cases are resistant to almost any treatment. Deep brain stimulation (DBS) holds promise as a new option for patients suffering from treatment-resistant chronic pain, but traditional approaches target only brain regions involved in one aspect of the pain experience and provide continuous 24/7 brain stimulation which may lose effect over time. By developing new technology that targets multiple, complimentary brain regions in an adaptive fashion, the investigators will test a new therapy for chronic pain that has potential for better, more enduring analgesia.

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Mount Sinai Researchers Identify Brain Protein That Promotes Maintenance of Chronic Pain

A protein called RGS4 (Regulator of G protein signaling 4) plays a prominent role in the maintenance of long-term pain states and may serve as a promising new target for the treatment of chronic pain conditions, accordin...
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Multisociety Pain Group Comments on Proposed Radiation Regulations in Colorado

AAPM participates in the Multisociety Pain Workgroup (MPW), a coalition of medical specialty societies, comprising physicians dedicated to pain management. This group convened to review and comment on the Colorado Board ...
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Objective Marker of Chronic Pain on the Horizon

Brain scans focusing on spatial variations in cerebral blood flow correlated with the presence -- though not severity -- of chronic knee pain, researchers said. The findings could eventually lead to a "brain signature of...
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BioElectronics Announces Publication of a Study of the ActiPatch® Medical Device as an Effective Long Term Treatment for Chronic Pain

 BioElectronics Corporation, the maker of non-invasive electroceutical devices, is pleased to announce the publication of a study in the journal Pain Research and Management , titled " A Prospective Six-Month S...
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Chronic Pain is a Huge Problem Nationwide, it’s Time for Fresh Approaches

  The medical community is turning to other approaches for chronic pain, including increasing patient support and education and improving overall wellness, perhaps with alternative treatments. Full story.

Noninvasive Nonpharmacological Treatments for Chronic Pain: An Update

The Evidence-based Practice Center (EPC) Program at the Agency for Healthcare Research and Quality (AHRQ) has posted the draft report for the systematic review on Noninvasive Nonpharmacological Treatments for Chronic Pai...
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Are Perioperative Interventions Effective in Preventing Chronic Pain After Primary Total Knee Replacement? A Systematic Review

For many people with advanced osteoarthritis, total knee replacement (TKR) is an effective treatment for relieving pain and improving function. Features of perioperative care may be associated with the adverse event of c...
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Tonic Suppression of the Mesolimbic Dopaminergic System by Enhanced Corticotropin-Releasing Factor Signaling Within the Bed Nucleus of the Stria Terminalis in Chronic Pain Model Rats

Although dysfunction of the mesolimbic dopaminergic system has been implicated in chronic pain, the underlying mechanisms remain to be elucidated. We hypothesized that increased inhibitory inputs to the neuronal pathway ...
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FDA Approves Abbott's "Low Dose," Recharge-Free Spinal Cord Stimulation System with up to Ten Year Battery Life for People Living with Chronic Pain

Abbott (NYSE: ABT) today announced the U.S. Food and Drug Administration (FDA) has approved the company's Proclaim XR™ recharge-free neurostimulation system for people living with chronic pain. The Proclaim XR platform o...
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Fighting Opioid Addiction and Chronic Pain Through Psychology

  AAPM members Magdalena Anitescu, MD, PhD, Madhuri Are, MD, Samer Narouze, MD, PhD , and Dennis J Patin, MD , are featured in this U.S. News and World Reports article: A Patient's Guide to Pain Management. Full sto...
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