Healthy People 2030 Sets Data-Driven National Objectives to Improve Health and Well-Being Over the Next Decade

About 1 in 12 adults in the United States have high-impact chronic pain. Healthy People 2030 focuses on helping people with high-impact chronic pain safely manage their pain and reduce its impact. View chronic pain objec...
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Medical Mindfulness: Virtual Reality Mindfulness Therapy for Anxiety and Pain Management in Patients With Acute and Chronic Pain

Adults and children undergoing medical care (inpatient or outpatient) often experience pain and anxiety either as a result of their medical condition or a side effect of medical procedures. The purpose of this study is t...
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Comparison of Patient-Reported Outcomes Measurement Information System and Legacy Instruments in Multiple Domains Among Older Veterans With Chronic Back Pain

Chronic low back pain (cLBP) results in significant physical, psycho-social and socioeconomic burden. Identifying efficient and reliable patient reported outcome measures is critical for research and clinical purposes. T...
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Maker of Mask Designed to Treat Chronic Pain Raises $5.8M

Sana masks reduce brain imbalances using audiovisual stimulation that leads to greater relaxation. They look similar to a virtual reality headset and use audio stimulation through headphones and visual stimulation with l...
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UC San Diego Health Offers New Treatment for Chronic Low Back Pain

AAPM Treasurer Farshad M. Ahadian, MD discusses a new minimally invasive approach to provide relief for patients suffering from chronic low back pain (CLBP). The new treatment is called "Intracept"— an outpatient procedu...
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Neuromodulation and Yoga for mTBI and Chronic Pain

The objectives of this VA SPiRE application are to develop a combined neuromodulation and yoga (iTBS+yoga) intervention for Veterans with mild traumatic brain injury (mTBI) and chronic pain, assess the intervention's fea...
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Patients Taking Opioids Produce Antibodies That May Hinder Anti-Opioid Vaccine

University of Wisconsin–Madison scientists have discovered that a majority of people they tested who were taking opioid painkillers for chronic back pain produced antibodies against the drugs that may contribute to some ...
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Exploring Metacognitions in Health Anxiety and Chronic Pain: A Cross-Sectional Survey

The occurrence of health anxiety (HA) in chronic pain is associated with adverse outcomes. As such, it is important to identify constructs that might influence HA and pain-related outcomes. Metacognitions are an emerging...
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Guidelines for Managing Chronic Cancer Pain: More Similar Than Not

AAPM member, Kenneth Candido, MD, comments on a comparative analysis published in the Journal of the National Comprehensive Cancer Network focusing on bridging the gap among clinical practice guidelines for pain manageme...
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CDC Opioid Workgroup Appoints AAPM Members

AAPM members Beth Darnall, PhD, and Mark Wallace, MD, were appointed to the Centers for Disease Control Opioid Workgroup by the Board of Scientific Counselors of the Centers for Disease Control and Prevention's National ...
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The Search for New, More Targeted Pain Treatments

AAPM member Mark S. Wallace, MD comments in this NIH Research Spotlight on the Helping to End Addiction Long-term (NIH HEAL) Initiative regarding what has been learned from clinical trials. Full story . 

FDA Approves Digital Health App for Chronic Pain Management

A new digital health tool has been approved by the U.S. Food and Drug Administration. The approval of the iOS-compatible application will enable individuals with chronic pain and movement disorders to receive personalize...
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AAPM Members Bernard Canlas, MD, and Erik Clarke, PhD, Receive NIH Grant

Congratulations to AAPM members Bernard Canlas, MD (left) and Erik Clarke, PhD (right) at VA Puget Sound who have just been awarded a $727,888 NIH grant. This is the first NIH-funded study at VA Puget Sound investigating...
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New PET/MRI Approach Pinpoints Chronic Pain Location, Alters Management

A new molecular imaging approach utilizing 18F-FDG positron emission tomography (PET) and magnetic resonance imaging (MRI) can precisely identify the location of pain generators in chronic pain sufferers, often precipita...
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First Scientific Study Using Virtual Reality to Treat Chronic Pain at Home Finds AppliedVR Platform Feasible, Scalable and Effective

AppliedVR, announced results from the first randomized controlled trial (RCT), evaluating virtual-reality-based (VR) therapy for self-management of chronic pain at home. The study, which was published in JMIR-FR, found t...
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Chronic Pain Master Protocol (CPMP): A Study of LY3016859 in Participants With Osteoarthritis

This study is being done to test the safety and efficacy of LY3016859 for the treatment of osteoarthritis pain. This trial is part of the chronic pain master protocol (H0P-MC-CPMP) which is a protocol to accelerate the d...
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Placebo Effect ‘Could Treat Pain’

Placebo pain-relief is reproducible in patients with chronic pain compared to healthy volunteers according to a unique University of Manchester study. In a research first, patients with high levels of psychological distr...
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New Therapy Reduces Chronic Low Back Pain in Large International Study

AAPM member John Markman, MD is the lead author of a new study that has found tanezumab, a monoclonal antibody that inhibits nerve activity, provides relief in patients with chronic low back pain, one of the leading reas...
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Treatment Effectiveness and Medication Use Reduction for Older Adults in Interdisciplinary Pain Rehabilitation

To examine the effectiveness of an interdisciplinary pain rehabilitation program (IPRP) that incorporates medication tapering on improving pain-related and performance-based outcomes for older adults with chronic noncanc...
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Case Series: Deep Brain Stimulation for Facial Pain

Deep brain stimulation (DBS) has been used for chronic pain for decades, but its use is limited due to a lack of reliable data about its efficacy for specific indications. Full story .

Delta Opioid Receptor Identified as Promising Therapeutic Target for Inflammatory Pain Relief

  Delta opioid receptors have a built-in mechanism for pain relief and can be precisely targeted with drug-delivering nanoparticles—making them a promising target for treating chronic inflammatory pain with fewer si...
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New Injection Techniques for Treating Chronic Foot Pain

  AAPM member Steven Richeimer, MD discusses new research that focused on the various injection techniques that are used for addressing chronic pain and how effective they are in alleviating chronic foot pain. Full ...
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Could Electrical Impulses Relieve Chronic Pain by Stimulating the Vagus Nerve?

A new microanatomical study investigated in detail spatial arrangements of the nerve fibers and blood vessels in the ear to position the electrodes in the ear. Until now, physicians had to rely on experience to place the...
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The Psychedelic Science of Pain

AAPM member Tim Furnish, MD discusses preliminary findings that indicate that psychedelics, alone or as part of multi-pronged treatment, can produce significant, meaningful and lasting reductions of chronic pain conditio...
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Weather Patterns Associated with Pain in Chronic-Pain Sufferers

The belief that weather influences people's health has been prevalent for millennia. Recent studies on the relationship between weather and pain for those who suffer from chronic pain remain indeterminate, with some stud...
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Chronic Pain Management During a Pandemic

This is an open-label cohort study of chronic pain patients referred to an interdisciplinary community outpatient clinic. The aim of this study is to determine whether video consultations are non-inferior to regular cons...
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The Comparative Effectiveness of Physical Exercise Interventions in Individuals With Chronic Non-Specific Neck Pain: Protocol for a Network Meta-Analysis

Neck pain is a global burdensome problem, with a large proportion of neck pain cases becoming chronic. Although physical exercise is a commonly prescribed treatment, the evidence on the effectiveness of isolated exercise...
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How to Manage Chronic Pain, Opioid Addiction During COVID-19

A Rutgers emergency medicine expert discusses challenges faced by chronic pain sufferers and people recovering from addiction during this period of social distancing. 

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Public Health Expert Discusses Potential Impact of COVID-19 Pandemic on Access to Recommended First-Line Treatments for Chronic Pain

An article published immediately before the COVID-19 pandemic found that non-pharmacological treatments were not being used by patients with chronic low back pain as often as recommended in the CDC and ACP guidelines. An...
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Guidance on Psychological Assessment and Management of Chronic Pain during the COVID-19 Crisis

In the context of the COVID-19 pandemic, people with pain may experience heightened pain intensity, and they may be at risk for pain-associated exacerbations in symptoms of depression, anxiety and PTSD, as well as family...
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Researchers are Developing Potential Treatment for Chronic Pain

Researchers from the University of Copenhagen have developed a new way to treat chronic pain which has been tested in mice. With a compound designed and developed by the researchers themselves, they can achieve complete ...
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Improving Care of Chronic Pain Patients with Spinal Cord Stimulator Therapy Amidst the Opioid Epidemic

The US government and other key stakeholders including professional medical bodies have amended recommendations in recent years to emphasize using no opioids or the lowest effective dose of opioids needed for treatment o...
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COVID-19 and Chronic Pain Survey Report

In order to better understand the challenges the pain community is facing and find ways to help, U.S. Pain Foundation recently conducted a survey of 664 individuals with pain about the impact of COVID-19.

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AHRQ Reports on Treatments for Chronic Pain

AHRQ completed three evidence reviews related to treatments for chronic pain. Final reports are available on the Effective Healthcare Website . Noninvasive Nonpharmacological Treatment for Chronic Pain (An Update) Nonopi...
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CDC Seeks Perspectives on Management of Acute and Chronic Pain

The Centers for Disease Control and Prevention is seeking stakeholders' perspectives on and experiences with pain and pain management, including, but not limited to, the benefits and harms of opioid use. CDC invites inpu...
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Loss of Nucleus Accumbens Low-Frequency Fluctuations Is a Signature of Chronic Pain

Chronic pain is a highly prevalent disease with poorly understood pathophysiology. In particular, the brain mechanisms mediating the transition from acute to chronic pain remain largely unknown. The authors identify a su...
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Appropriate Referral and Selection of Patients with Chronic Pain for Spinal Cord Stimulation: European Consensus Recommendations and E‐Health Tool

Spinal cord stimulation (SCS) is an established treatment for chronic neuropathic, neuropathic‐like and ischaemic pain. However, the heterogeneity of patients in daily clinical practice makes it often challenging to dete...
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Key Chronic Low Back Pain Outcomes Remain Stable Over Time

A Journal of General Internal Medicine article, provided some insight into why chronic low back pain may be difficult to treat. Data published from the PRECISION Pain Research Registry, which looked at 289 chronic low ba...
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Six Building Blocks: A Team-Based Approach to Improving Opioid Management in Primary Care

The Agency for Healthcare Research and Quality released a toolkit offering a structured team-based approach designed to support clinics as they independently implement effective, guideline-driven care for their patients ...
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A Behavioral Intervention for Depression and Chronic Pain in Primary Care

Chronic pain and depression frequently co-exist in late and mid-life and contribute to increased disability, high health care costs, psychiatric comorbidity, and suicide. Older and middle-aged depressed-pain patients: a)...
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Behavioral Activation and Behavioral Inhibition: An Examination of Function in Chronic Pain

The objective of the study was to examine the BIS-BAS model of chronic pain. This model posits that 2 neurophysiological systems-the behavioral inhibition system (BIS) sensitized to and activated by punishment cues and t...
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AAPM Member Discusses Challenges of Treating Chronic Pain Patients Amidst Opioid Crisis

"We're de-prescribing without having sufficient evidence on how to do this the right way, how to protect patients," says AAPM member, Beth Darnall, PhD , in a recent Guardian Australia interview. Full story .

AAPM Members Discuss Clinical Challenges to Opioid Tapering in MedPage Today

AAPM members Beth Darnall, PhD , and W. Michael Hooten, MD , contributed to this MedPage Today article, Clinical Challenge: Opioid Tapering—New trials look at ways to help chronic pain patients take fewer drugs. Full sto...
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Can Pain Management be Safely Optimized in Older Adults?

Managing chronic pain is a challenging task. Older adults (OAs) (>65 years) are the fastest growing segment of our population, and are substantially affected by chronic pain of various etiologies. Read the abstract .&...
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Let It Be: Mindful Acceptance Down-Regulates Pain and Negative Emotion

Mindfulness training ameliorates clinical and self-report measures of depression and chronic pain, but its use as an emotion regulation strategy—in individuals who do not meditate—remains understudied. Read the abstract ...
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Psychologist Uses Computer-Simulated Patients to Untangle Sociological Influences in Pain Care

In a recent study published in the journal Pain , researchers found that white physicians who self-scored higher on "intergroup anxiety" -- discomfort during interactions with groups who share fewer similar characteristi...
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FDA Accepts Regulatory Submission for Tanezumab, a Potential First-in-Class Treatment for Patients with Chronic Pain Due to Moderate-to-Severe Osteoarthritis

​ Read the full story . 
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Association of Tramadol Use with Risk of Hip Fracture

Several professional organizations have recommended tramadol as one of the first-line or second-line therapies for patients with chronic noncancer pain and its prescription has been increasing rapidly worldwide; however, the safety profile of tramadol, such as risk of fracture, remains unclear.

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AAPM Members Contribute to HuffPost Article: How to Talk to Your Doctor If You're Experiencing Chronic Pain

AAPM Members Sara Davin, PhD and David Edwards, MD PhD were interviewed by Huffington Post about why it can be difficult to identify chronic pain treatments that work and how persons experiencing pain can communicate mos...
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T'ai Chi for Chronic Low Back Pain in Older Adults: A Feasibility Trial

T'ai chi (TC) has been found effective for improving chronic low back pain. However, such studies did not include adults over 65 years of age. This study was designed to evaluate the feasibility and acceptability of TC in this population compared with Health Education and with Usual Care.

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