AAPM 2020 Scientific Poster Abstracts Published in Pain Medicine

Scientific poster abstracts that were presented during AAPM 2020 earlier this year in National Harbor, MD, are now accessible in the Academy's journal, Pain Medicine . The call for AAPM 2021 poster abstracts will open in...
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Effect of Yoga as Add-On Therapy in Migraine

This abstract evaluated the effectiveness of yoga as an adjuvant to conventional medical management on clinical outcomes in patients with migraine. 

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Sigma-1 Receptor Activity in Primary Sensory Neurons Is a Critical Driver of Neuropathic Pain

The Sigma-1 receptor (σ1R) is highly expressed in the primary sensory neurons (PSNs) that are the critical site of initiation and maintenance of pain following peripheral nerve injury.  

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The Comparative Effectiveness of Physical Exercise Interventions in Individuals With Chronic Non-Specific Neck Pain: Protocol for a Network Meta-Analysis

Neck pain is a global burdensome problem, with a large proportion of neck pain cases becoming chronic. Although physical exercise is a commonly prescribed treatment, the evidence on the effectiveness of isolated exercise...
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Ketamine for Migraine in the Emergency Department

Ketamine is utilized often in the emergency department (ED) for rapid sequence intubation, procedural sedation, and acute pain management. The treatment of migraine headache in the ED varies widely and is dependent on se...
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Impact Of Long-Term Buprenorphine Treatment On Adverse Health Care Outcomes In Medicaid

The optimal, or even minimum, duration of medication treatment for opioid use disorder (OUD) needed to improve long-term outcomes has not been established empirically. As a result, health plans set potentially restrictiv...
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Improving Care of Chronic Pain Patients with Spinal Cord Stimulator Therapy Amidst the Opioid Epidemic

The US government and other key stakeholders including professional medical bodies have amended recommendations in recent years to emphasize using no opioids or the lowest effective dose of opioids needed for treatment o...
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Opioid Use to Treat Migraine Headaches in Hospitalized Children and Adolescents

Prescription of opioids to treat pediatric migraine is explicitly discouraged by treatment guidelines but persists in some clinical settings. We sought to describe rates of opioid administration in pediatric migraine hos...
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Examination and Characterization of Burst Spinal Cord Stimulation on Cerebrospinal Fluid Cellular and Protein Constituents in Patient Responders with Chronic Neuropathic Pain: A Pilot Study

Patients with neuropathic pain have altered proteomic and neuropeptide constituents in cerebrospinal fluid (CSF) compared to controls. Tonic spinal cord stimulation (SCS) has demonstrated differential expression of neuro...
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Reliability and Construct Validity of a Composite Pain Scale for Rabbit (CANCRS) in a Clinical Environment

A composite pain scale for assessing and quantifying pain in rabbits (CANCRS) has been designed merging the Rabbit Grimace Scale (RbtGS) and a scale including clinical parameters (CPS). Construct validity and inter-rater...
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Hydromorphone Unit Dose Affects Intraoperative Dosing: An Observational Study

Although clinical factors related to intraoperative opioid administration have been described, there is little research evaluating whether administration is influenced by drug formulation and, specifically, the unit dose...
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Pregabalin and Gabapentin for Pain

Pregabalin and gabapentin can be effective as first line treatment for some people with neuropathic pain such as post-herpetic neuralgia and diabetic peripheral neuropathy.

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Targeting Neurotrophic Factors: Novel Approaches to Musculoskeletal Pain

Chronic pain represents a substantial unmet medical need globally. In recent years, the quest for a new generation of novel, safe, mechanism-based analgesic treatments has focused on neurotrophic factors, a large group o...
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Loss of Nucleus Accumbens Low-Frequency Fluctuations Is a Signature of Chronic Pain

Chronic pain is a highly prevalent disease with poorly understood pathophysiology. In particular, the brain mechanisms mediating the transition from acute to chronic pain remain largely unknown. The authors identify a su...
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Unmet Needs in the Acute Treatment of Migraine Attacks and the Emerging Role of Calcitonin Gene–Related Peptide Receptor Antagonists

Migraine is a prevalent and chronic disease associated with high rates of disability and significant financial and socioeconomic burden. Current acute treatments for migraine attacks include both migraine-specific a...
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Complementary and Alternative Medicine for Postoperative Pain: A Systematic Review

The treatment of postoperative pain is an ongoing challenge for orthopaedic surgeons. Poorly controlled pain is associated with poorer patient outcomes, and the prescription of opioids may lead to prolonged, nonmedical u...
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Peripheral Trigeminal Branch Stimulation for Refractory Facial Pain: A Single-Center Experience

Facial pain refractory to medical treatments may benefit from neurosurgical interventions. Only a few studies have reported on the efficacy of peripheral trigeminal stimulation and more specifically supraorbital nerve (S...
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Spinal Glia and Proinflammatory Cytokines Mediate Mirror-Image Neuropathic Pain in Rats

Mirror-image allodynia is a mysterious phenomenon that occurs in association with many clinical pain syndromes. Allodynia refers to pain in response to light touch/pressure stimuli, which normally are perceived as innocu...
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Manual Acupuncture for Migraine

The same pathways that transmit the caress of a lover can backfire and cause neuropathic pain. This pain is due to damage or disease affecting the sensory systems. Migraine is one of the most common and disabling ne...
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Mapping Cannabis Potency in Medical and Recreational Programs in the United States

Cannabis related online searches are associated with positive attitudes toward medical cannabis, particularly when information is obtained from dispensaries.

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Association of Intermittent and Constant Knee Pain Patterns With Knee Pain Severity, Radiographic Knee Osteoarthritis Duration and Severity

The objective of this study was to examine the relation of knee pain patterns to pain severity, and to radiographic osteoarthritis (OA) severity and duration. 

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A Comprehensive Review of Over-The-Counter Treatment for Chronic Migraine Headaches

Migraine headaches are a neurologic disorder characterized by attacks of moderate to severe throbbing headache that are typically unilateral, exacerbated by physical activity, and associated with phonophobia, photophobia...
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Perioperative Point of Care Ultrasound (POCUS) for Anesthesiologists: An Overview

Point of care ultrasound (POCUS) has played a role across almost every medical specialty. Although anesthesiologists have been using bedside ultrasound for nerve blocks and vascular access for many years now, there has b...
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Surgery Versus Conservative Care for Persistent Sciatica Lasting 4 to 12 Months

The treatment of chronic sciatica caused by herniation of a lumbar disk has not been well studied in comparison with acute disk herniation. Data are needed on whether diskectomy or a conservative approach is better for s...
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Acupuncture for Pediatric Sickle Cell Pain Management: A Promising Non-Opioid Therapy

The objective of this study is to describe the use of acupuncture for pain management in children with sickle cell disease. 

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IL-4 Induces M2 Macrophages to Produce Sustained Analgesia Via Opioids

IL-4 is a pleiotropic antiinflammatory cytokine, which can be neuroprotective after nervous system injury. The beneficial actions of IL-4 are thought to result from the blunting of action of inflammatory mediators, such ...
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Association of Opioid Use with Pain and Satisfaction After Dental Extraction

Dentists commonly prescribe opioids to relieve pain after tooth extraction. Understanding the differences in patient-reported outcomes between opioid users and nonusers could encourage the adoption of more conservative a...
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Smartphone Use and Primary Headache

The objective of this study is to determine the association of smartphone use with occurrence of new-onset headache and/or increased severity of headaches in patients with primary headache.  Read the abstract . ...
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Behavioral Activation and Behavioral Inhibition: An Examination of Function in Chronic Pain

The objective of the study was to examine the BIS-BAS model of chronic pain. This model posits that 2 neurophysiological systems-the behavioral inhibition system (BIS) sensitized to and activated by punishment cues and t...
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Depression and Functional Outcomes in Patients Presenting to the Emergency Department With Low Back Pain

Low back pain (LBP) is a common reason for patients to present to Emergency Departments (EDs). Our objective was to describe the associations between depressive symptoms, pain severity, and functional impairment up to 3 ...
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Improving Osteoarthritis Care by Digital Means - Effects of a Digital Self-Management Program after 24- or 48-Weeks of Treatment.

Osteoarthritis (OA) is highly prevalent in older adults and a growing cause of disability. Easily accessible first-line treatment of OA is increasingly important. Digital self-management programs have in recent years bec...
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Associations Between Stopping Prescriptions for Opioids, Length of Opioid Treatment, and Overdose or Suicide Deaths in US Veterans: Observational Evaluation

The objective of this study is to examine the associations between stopping treatment with opioids, length of treatment, and death from overdose or suicide in the Veterans Health Administration.  Read the abstract ....
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Can Pain Management be Safely Optimized in Older Adults?

Managing chronic pain is a challenging task. Older adults (OAs) (>65 years) are the fastest growing segment of our population, and are substantially affected by chronic pain of various etiologies. Read the abstract .&...
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3D Printed Opioid Medicines with Alcohol-Resistant and Abuse-Deterrent Properties

In the past decade, prescriptions for opioid medicines have been exponentially increasing, instigating opioid abuse as a global health crisis associated with high morbidity and mortality. Read the abstract . 
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Let It Be: Mindful Acceptance Down-Regulates Pain and Negative Emotion

Mindfulness training ameliorates clinical and self-report measures of depression and chronic pain, but its use as an emotion regulation strategy—in individuals who do not meditate—remains understudied. Read the abstract ...
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Quality Improvement in Dementia Care

The Dementia Management Quality Measurement Set was first developed and released in 2013 by the PCPI Foundation. Developed by an appointed multistakeholder technical expert panel (TEP), the 2013 Measurement Set was suppo...
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Association of Tramadol Use with Risk of Hip Fracture

Several professional organizations have recommended tramadol as one of the first-line or second-line therapies for patients with chronic noncancer pain and its prescription has been increasing rapidly worldwide; however, the safety profile of tramadol, such as risk of fracture, remains unclear.

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T'ai Chi for Chronic Low Back Pain in Older Adults: A Feasibility Trial

T'ai chi (TC) has been found effective for improving chronic low back pain. However, such studies did not include adults over 65 years of age. This study was designed to evaluate the feasibility and acceptability of TC in this population compared with Health Education and with Usual Care.

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Efficacy, Safety, and Acceptability of Pharmacologic Treatments for Pediatric Migraine Prophylaxis: A Systematic Review and Network Meta-Analysis

 What are the most effective, safe, and accepted pharmacologic treatments for migraine prophylaxis in children and adolescents?

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Does Vitamin D Status Influence Lumbar Disc Degeneration and Low Back Pain in Postmenopausal Women? A Retrospective Single-Center Study

The objective of this study was to investigate the relationship between serum vitamin D concentration and lumbar disc degeneration (LDD) in postmenopausal women and the epidemiologic factors affecting low back pain (LBP). 

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Cost-Effectiveness Model Shows Superiority of Wireless Spinal Cord Stimulation Implantation Without a Separate Trial

The authors in this study evaluated the cost-effectiveness of wireless spinal cord stimulation (Wireless SCS) with single stage "direct to permanent" implantation vs. screening with temporary electrodes and an external pulse generator followed by implantation of a system for long-term use (IPG SCS). 

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Cutaneous Nerve Fields of the Anteromedial Lower Limb-Determination With Selective Ultrasound-Guided Nerve Blockade

This study aimed to determine the peripheral cutaneous nerve fields (CNF), their variability, and potential overlap by selectively blocking the intermediate (IFCN) and medial (MFCN) femoral cutaneous nerves and the infrapatellar branch of the saphenous nerve (IPBSN) in healthy volunteers.

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Magnetic Resonance Imaging of Neuroinflammation in Chronic Pain: A Role for Astrogliosis?

Non-invasive measures of neuroinflammatory processes in humans could substantially aid diagnosis and therapeutic development for many disorders, including chronic pain. Several proton Magnetic Resonance Spectroscopy (H-M...
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A Systematic Review of the Evidence for the Efficacy of Opioids for Chronic Non-Cancer Pain in Community-Dwelling Older Adults

The ageing global population and concomitant increase in the use of opioid analgesia have highlighted the need to evaluate the effectiveness of opioids for chronic pain in older people.

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Perturbing the Activity of the Superior Temporal Gyrus During Pain Encoding Prevents the Exaggeration of Pain Memories: A Virtual Lesion Study Using Single-Pulse Transcranial Magnetic Stimulation

Past studies have shown that pain memories are often inaccurate, a phenomenon known as mnemonic pain bias. Pain memories are thought to play an important role on how future pain is felt. Recent evidence from our laborato...
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Does Experimentally Induced Pain-Related Fear Influence Central and Peripheral Movement Preparation in Healthy People and Low Back Pain Patients?

Non-specific chronic low back pain (CLBP) is a multifactorial disorder. Pain-related fear and altered movement preparation are considered to be key factors in the chronification process. Interactions between both have be...
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Evaluation and Treatment Patterns of New Low Back Pain Episodes for Elderly Adults in the United States, 2011–2014

New low back pain (LBP) is a common outpatient complaint. Little is known about how care is delivered over the course of a year to patients who develop new LBP and whether such care patterns are guideline-concordant.

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Preemptive Pain Management Program Is Associated with Reduction of Opioid Prescriptions After Benign Minimally Invasive Foregut Surgery

The opioid crisis is partly due to opioids prescribed after elective surgery. This study sought to determine if a preemptive pain-management program would be associated with opioid-free discharge after benign foregut surgery.

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Neural and Sociocultural Mediators of Ethnic Differences in Pain

Understanding ethnic differences in pain is important for addressing disparities in pain care. A common belief is that African Americans are hyposensitive to pain compared to Whites, but African Americans show increased ...
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Call for Late-Breaking Poster Abstracts Live through January 6, 12 pm CT

Submit late-breaking scientific poster abstracts for possible publication Pain Medicine and presentation at the AAPM 36th Annual Meeting, February 27-March 1, 2020, in National Harbor, MD. 

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