TENS Efficacy on Acute Back Pain in an Emergency Department Triage

Transcutaneous Electrical Nerve Stimulation (TENS) devices produce a gentle electrical stimulation that when applied through pads applied directly to the skin, has a noticeable effect in reducing pain associated with various types of injuries and ailments.

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Neoline Is the Active Ingredient of Processed Aconite Root Against Murine Peripheral Neuropathic Pain Model, and Its Pharmacokinetics in Rats

 The present study investigated the effects of PA on a murine peripheral neuropathy model induced by intraperitoneal injection of paclitaxel and partial ligation of the sciatic nerve (Seltzer model), and identified its active ingredients.
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TRP Channels and Migraine: Recent Developments and New Therapeutic Opportunities.

Migraine is the second-most disabling disease worldwide, and the second most common neurological disorder. Attacks can last many hours or days, and consist of multiple symptoms including headache, nausea, vomiting, hypersensitivity to stimuli such as light and sound, and in some cases, an aura is present.

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Insular and Anterior Cingulate Cortex Deep Stimulation for Central Neuropathic Pain: Disassembling the Percept of Pain.

Objective: To compare the analgesic effects of stimulation of the anterior cingulate cortex (ACC) or the posterior superior insula (PSI) against sham deep (d) repetitive (r) transcranial magnetic stimulation (TMS) in patients with central neuropathic pain (CNP) after stroke or spinal cord injury in a randomized, double-blinded, sham-controlled, 3-arm parallel study. 

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TRPV1 promotes opioid analgesia during inflammation

 Abstract: Pain and inflammation are inherently linked responses to injury, infection, or chronic diseases. Given that acute inflammation in humans or mice enhances the analgesic properties of opioids, there is much interest in determining the inflammatory transducers that prime opioid receptor signaling in primary afferent nociceptors.

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A Shot at Blocking Addiction

With the help of a NIH grant, University of New Mexico researchers are developing a vaccine that would block opioids from acting in the brain, a treatment that could play a key role in overcoming addiction. 

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Social Support Key to Remission from Suicidal Thoughts for Disabling Chronic Pain Sufferers

According to a new study, poverty and history of anxiety and depressive disorders were impediments to recovery from suicidal ideation. 

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New Part D Opioid Overutilization Policies

CMS implemented new opioid policies for Medicare drug plans effective January 1, 2019. Medicare Part D enrollees who have not filled an opioid prescription recently (within the last 60 days) will be limited to up to a 7-...
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AAPM35 On Demand Course Recordings Now Posted

Thank you to all of the faculty, attendees, and industry partners who contributed to the success of the AAPM 35th Annual Meeting & Preconferences held in Denver March 6-10, 2019. The following on demand courses that ...
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AAPM Comments on AHRQ Key Questions for Systematic Review on Management of Primary Headaches in Pregnancy

Comments from the American Academy of Pain Medicine The American Academy of Pain Medicine thanks the Agency for the opportunity to comment on The Evidence-based Practice Center Program at the Agency for Healthcare Resear...
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