Researchers are Developing Potential Treatment for Chronic Pain

Researchers from the University of Copenhagen have developed a new way to treat chronic pain which has been tested in mice. With a compound designed and developed by the researchers themselves, they can achieve complete ...
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How Animals 'Dial-Up' the Pain They Experience from Certain Stimuli

Researchers in the Faculty of Biological Sciences, in collaboration with colleagues in the US and China, have discovered that, under certain conditions, the molecular sensors that respond to physical stimuli can be turbo...
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Researchers Identify Potential Pathway to Make Opioids Safer, More Effective

Findings from a study by UArizona College of Medicine – Tucson suggest heat shock protein 90 inhibitors could give doctors the opportunity to implement a dose-reduction strategy for patients. Less opioid drug could be pr...
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NIH Convenes Virtual Consortium on Advances in Pain Research

On June 3, the NIH Pain Consortium will convene the 15th Annual NIH Pain Consortium Symposium on Advances in Pain Research as an all-virtual WebEx event. The symposium, " Technologies for Improved Understanding and Manag...
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Ketamine for Migraine in the Emergency Department

Ketamine is utilized often in the emergency department (ED) for rapid sequence intubation, procedural sedation, and acute pain management. The treatment of migraine headache in the ED varies widely and is dependent on se...
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Impact Of Long-Term Buprenorphine Treatment On Adverse Health Care Outcomes In Medicaid

The optimal, or even minimum, duration of medication treatment for opioid use disorder (OUD) needed to improve long-term outcomes has not been established empirically. As a result, health plans set potentially restrictiv...
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Improving Care of Chronic Pain Patients with Spinal Cord Stimulator Therapy Amidst the Opioid Epidemic

The US government and other key stakeholders including professional medical bodies have amended recommendations in recent years to emphasize using no opioids or the lowest effective dose of opioids needed for treatment o...
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Opioid Use to Treat Migraine Headaches in Hospitalized Children and Adolescents

Prescription of opioids to treat pediatric migraine is explicitly discouraged by treatment guidelines but persists in some clinical settings. We sought to describe rates of opioid administration in pediatric migraine hos...
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Investigate the Mechanisms, Predictors, and Prevention of Persistent Post-Traumatic Headache

This is a United States Department of Defense funded Focused Program study that aims to identify mechanisms and predictors for persistent of post-traumatic headache attributed to mild traumatic brain injury, and identify...
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Examination and Characterization of Burst Spinal Cord Stimulation on Cerebrospinal Fluid Cellular and Protein Constituents in Patient Responders with Chronic Neuropathic Pain: A Pilot Study

Patients with neuropathic pain have altered proteomic and neuropeptide constituents in cerebrospinal fluid (CSF) compared to controls. Tonic spinal cord stimulation (SCS) has demonstrated differential expression of neuro...
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