Hyperactivity of Anterior Cingulate Cortex Areas 24a/24b Drives Chronic Pain-Induced Anxiodepressive-Like Consequences

Source: Journal of Neuroscience Abstract: Pain associates both sensory and emotional aversive components, and often leads to anxiety and depression when it becomes chronic. Here, we characterized, in a mouse model, the l...
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Hydroxychloroquine Effectiveness in Reducing Symptoms of Hand Osteoarthritis: A Randomized Trial

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Combination Pharmacotherapy for the Treatment of Fibromyalgia in Adults

[Source: The Cochrane Library] Abstract: Background: Fibromyalgia is a chronic widespread pain condition affecting millions of people worldwide. Current pharmacotherapies are often ineffective and poorly tolerated. Combi...
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Patient-Centered Prescription Opioid Tapering in Community Outpatients with Chronic Pain

Source: JAMA Internal Medicine Beth D. Darnall, PhD; Maisa S. Ziadni, PhD; Richard L. Stieg, MD, MPH; Ian G. Mackey; Ming-Chih Kao, PhD, MD; Pamela Flood, MD, PhD Abstract: The risks associated with prescription opioids ...
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Neuroinflammation and Central Sensitization in Chronic and Widespread Pain

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In the Opioid Crisis, Military Research May Protect Citizens and Warfighters

Source: Armed with Science DOD Blog Ten thousand times more potent than morphine, the drug carfentanil poses a risk to both civilians and warfighters. The powerful opioid, with lethal amounts smaller than a poppy seed, w...
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Pilot Study in Kenya Shows Link Between Chronic Pain and Glutamate Consumption

Source: American University Preliminary research from a small pilot study carried out in Meru, in eastern Kenya, shows a link between chronic pain and consumption of glutamate, a common flavor enhancer found in Western a...
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A Qualitative Analysis of Gabapentin Misuse and Diversion Among People Who Use Drugs in Appalachian Kentucky

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New Guideline Warns Pain Benefits of Medical Cannabis Overstated

Source: University of Alberta Faculty of Medicine & Dentistry A new medical guideline suggests Canada's family physicians should take a sober second thought before prescribing medical cannabis to most patients. Publi...
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FDA Advisory Committee Nixes Novel Pain Drug

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