Transcription Factor Sp4 Is Required for Hyperalgesic State Persistence

Understanding how painful hypersensitive states develop and persist beyond the initial hours to days is critically important in the effort to devise strategies to prevent and/or reverse chronic painful states. Read the a...
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Medtronic Announces FDA Clearance and U.S. Launch of the Accurian Radio Frequency System for Nerve Tissue Ablation

​ Medtronic plc (NYSE:MDT) today announced U.S. Food and Drug Administration (FDA) 510(k) clearance of the Accurian(TM) RF ablation platform, which conducts radio frequency (RF) ablation of nerve tissues. RF ablatio...
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Peer-Support, Healing Hands Offers New Options to Patients with Chronic Pain on Prescription Opioids

A program providing group support, acupuncture, mindfulness, massage and gentle exercise may offer safe, extra relief to patients on prescription opioids, according to a study led by researchers at UC San Francisco. Full...
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Acupuncture Relief for Chronic Neck Pain (NCT03859011)

This study will measure the effectiveness of "usual care" for chronic neck pain as defined in the protocol, compared with usual care plus acupuncture for chronic neck pain. This study's hypothesis is that combining acupu...
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Glial Ensheathment of the Somatodendritic Compartment Regulates Sensory Neuron Structure and Activity

Sensory neurons perceive environmental cues and are important of organismal survival. Peripheral sensory neurons interact intimately with glial cells. While the function of axonal ensheathment by glia is well studied, le...
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Subacromial Decompression Surgery for Adults with Shoulder Pain: A Clinical Practice Guideline

Do adults with atraumatic shoulder pain for more than 3 months diagnosed as subacromial pain syndrome (SAPS), also labelled as rotator cuff disease, benefit from subacromial decompression surgery? This guideline builds o...
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Interdisciplinary Pain Management Approach May Reduce Opioid and Benzodiazepine Use in Chronic Pain Patients

A four-week interdisciplinary pain management program for worker's compensation patients with chronic pain significantly reduced their opioid and benzodiazepine use, according to a new study.

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HEAL Initiative: Coordinating Center to Support NIDA Preventing Opioid Use Disorder in Older Adolescents and Young Adults (Ages 16–30) Initiative

As part of the NIH Helping to End Addictions Long-term (HEAL) initiative to speed development and implementation of scientific solutions to the national public health opioid crisis, NIDA is seeking cooperative agreement ...
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Smokers Are At High Risk for Low Back Pain, Hospitalization, and Opioid Use

Smokers are at high risk for low back pain, and also have higher rates of healthcare utilization and opioid use, and physicians should ask these patients about other comorbidities that may make their pain treatment more ...
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Virtual Reality Intervention Shows Promise for Back Pain Patients Who Are Afraid to be Active

A new virtual reality physical activity intervention may be effective for people with chronic low back pain who avoid activity because of fear, helping them to become physically active once again, according to a new stud...
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