Persistent Headache or Back Pain ‘Twice as Likely’ in the Presence of the Other

Researchers suggest the possibility of an underpinning biological relationship between people with persistent headache and back pain, which could be a target for treatment.  Full story.

Multidisciplinary Translational Approach to Investigate Mechanisms Predictors & Prevention of Persistent PTH

Study Description: Brief Summary: This is a United States Department of Defense funded Focused Program study that aims to identify mechanisms and predictors for persistent of post-traumatic headache attributed to mild tr...
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Headache in Petrous Apicitis: A Case Report of Chronic Migraine-like Headache Due to Peripheral Pathology

 AbstractObjective: To report a case of petrous apicitis that manifested as chronic migraine without aura and to discuss the pathophysiological mechanisms behind this presentation. Background:Petrous apicitis is a r...
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An Evolutionary Medicine Perspective on Pain and Its Disorders

Abstract: Enormous progress in understanding the mechanisms that mediate pain can be augmented by an evolutionary medicine perspective on how the capacity for pain gives selective advantages, the trade-offs that shaped t...
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Telepsychiatry Helps Recruitment and Patient Care in Rural Areas

It used to take at least nine months for a patient to schedule an initial appointment with a psychiatrist at Meridian Health Services in Indiana. Now, it takes days, thanks to a program that allows doctors to connect ove...
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Psychiatric Disorders and Pain

Two new studies in Pain Medicine highlight the importance of addressing mental health problems in patients with pain. Full story.
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Exercising To Ease Pain: Taking Brisk Walks Can Help

Researchers shows no difference in pain perception after exercise for those who walked just three times a week. However, for the people who exercised five times or more each week, they reported 60% less pain perception t...
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Efficacy and Safety of VM202 in Painful Diabetic Peripheral Neuropathy - The HOPES Trial

Study Description: Brief Summary: A double-blind, randomized, placebo-controlled, single-center, 12-month phase 2 study designed to assess the safety and efficacy of VM202 as a replacement for opioid analgesics in opioid...
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Euphorbia Bicolor (Euphorbiaceae) Latex Phytochemicals Induce Long-Lasting Non-Opioid Peripheral Analgesia in a Rat Model of Inflammatory Pain

The negative side effects of opioid-based narcotics underscore the search for alternative non-opioid bioactive compounds that act on the peripheral nervous system to avoid central nervous system-mediated side effects. Th...
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Rethinking Opioid Dose Tapering, Prescription Opioid Dependence, and Indications for Buprenorphine

The expanded use of opioids for chronic pain has created a population of patients prescribed long-term opioid therapy lasting years or decades. Doses are often above the thresholds suggested in the 2016 Centers for Disea...
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