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November 11, 2019

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Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain

 Brief Summary:Chronic pain affects 1 in 4 US adults, and many cases are resistant to almost any treatment. Deep brain stimulation (DBS) holds promise as a new option for patients suffering from treatment-resistant chronic pain, but traditional approaches target only brain regions involved in one aspect of the pain experience and provide continuous 24/7 brain stimulation which may lose effect over time. By developing new technology that targets multiple, complimentary brain regions in an adaptive fashion, the investigators will test a new therapy for chronic pain that has potential for better, more enduring analgesia.

Trends in Prescription Opioid Use and Dose Trajectories Before Opioid Use Disorder or Overdose in US Adults From 2006 to 2016: A Cross-Sectional Study

With governments’ increasing efforts to curb opioid prescription use and limit dose below the Centers for Disease Control and Prevention (CDC)-recommended threshold of 90 morphine milligram equivalents per day, little is known about prescription opioid patterns preceding opioid use disorder (OUD) or overdose.

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Pain Medicine Journal
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AAPM

American Academy of Pain Medicine