Brief Summary: This is a multi-center, prospective, open-label, single-arm, observational, feasibility study. The goal of this study is to determine the feasibility of intra-spinal stimulation with optimal paresthesia coverage therapy for chronic pain relief in patients with complex regional pain syndrome type I or causalgia. Up to 20 patients with intractable chronic severe limb pain associated with complex regional pain syndrome (CRPS) will be included in the study. A standard of care trial phase to test a subjects’ response to Intraspinal-Optimal Stim therapy will be conducted during a 3 to 10-day period. Patients that obtain 50% or greater pain relief during the trial period will undergo permanent implantation of the device. Primary outcome will evaluate pain response at 3 months of therapy, based on NPRS pain score relative to baseline. Patients will be followed up for 6 months after the start of therapy.
Facing an urgent need for safer and more effective therapies for those suffering from debilitating pain, Saint Louis University researchers are on a mission to find a non-narcotic off-switch for pain.
Researchers at University of California San Diego School of Medicine have identified specific regions of the brain that drive, influence, and moderate depressive mood and its relationship to perceiving physical pain.
Despite the availability of therapies, many headache syndromes remain refractory to symptomatic treatment, achieving incomplete resolution of pain, and patients with chronic headaches often pursue nonpharmacologic treatments in hopes of achieving a greater duration of pain relief.
American Academy of Pain Medicine