We compare intranasal ketamine with intranasal placebo in providing pain reduction at 30 minutes when added to usual paramedic care with nitrous oxide. Methods: This was a randomized double-blind study of out-of-hospital patients with acute pain who reported a verbal numeric rating scale (VNRS) pain score greater than or equal to 5. Exclusion criteria were younger than 18 years, known ketamine intolerance, nontraumatic chest pain, altered mental status, pregnancy, and nasal occlusion. Patients received usual paramedic care and were randomized to receive either intranasal ketamine or intranasal saline solution at 0.75 mg/kg.
The Forum on Neuroscience and Nervous System Disorders and Global Forum on Innovation in Health Professional Education hosted a public workshop that discussed the state of evidence on the effectiveness of nonpharmacological treatments and integrative health models for pain management, multimodal approaches, and research gaps and key questions for further research.
Hospital program offers intensive physical and occupational therapy, relaxation techniques, stress-management training, and music and therapeutic art to help manage Amplified Pain Syndrome.
American Academy of Pain Medicine