Major depression, obesity and chronic pain are all linked to the effects of one protein, called FKBP51. Researchers have now developed a highly selective compound that can effectively block FKBP51 in mice, relieving chronic pain [...]
Scientists report that they are developing single-dose, longer-lasting opioid antidotes using polymer nanoparticles. Full story.
A rare disorder in which a 71-year-old woman experiences no pain or anxiety, raises questions about the links between physical and psychological pain. Full story.
In a research letter in the new issue of JAMA Surgery, a team from the University of Michigan reports that providing special disposal bags doubled the percentage of patients who safely disposed of their unneeded [...]
Pairing music with ibuprofen improved analgesic outcomes in an inflammation pain mouse model by more than 90 percent, while the cannabidiol-music and galanin analog NAX 5055-music pairings significantly reduced inflammation by 70 percent. Full story.
Many people who use opioid medications long term do not produce enough testosterone or another important hormone, cortisol, according to a new study. Full story.
Enhanced recovery after surgery (ERAS) is a multidimensional approach to improving the care of surgical patients using subspecialty- and procedure-specific evidence-based protocols. The literature provides evidence of the benefits of ERAS implementation, which include expedited [...]
Researchers have designed a therapeutic robot that simulates human skin-to-skin contact, helping reduce pain for babies in the neonatal intensive care unit. Full story.
Transmucosal immediate-release fentanyl (TIRF) drugs are potent, rapid-acting opioids approved to treat breakthrough pain in patients with cancer who are tolerant to other around-the-clock opioid analgesics. In March 2012, a US Food and Drug Administration–approved [...]
A clinical trial of an experimental drug designed to treat cravings associated with OUD has begun in the National Institutes of Health Clinical Center. The Phase I trial in healthy adults will assess the safety [...]
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